Vanessa Van den Linden, Assistance Association for Disabled Children

Moderator: Nicole Chavez, Communications Consultant

Fine Mapping for Genetic Susceptibility to Valproic Acid-Induced Exencephaly in Mice
Lei Y, Wlodarczyk BJ, Cabrera RM, Finnell RH. Dell Medical School, Austin, TX, United States.

In Utero Exposure to the Pesticide Synergist and Sonic Hedgehog Signaling Inhibitor Piperonyl Butoxide Causes Holoprosencephaly in Mice
Everson JL, Lipinski RJ. University of Wisconsin–Madison, Madison, WI, United States.

Gene-Environment Interactions in Holoprosencephaly
Muenke M¹, Kruszka P¹, Addissie Y¹, Troia A², Kozel B², Everson J³, Malecki K⁴, Lipinski R³.
¹National Human Genome Research Institute, NIH, Bethesda, MD, United States, ²National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, United States, ³Department of Comparative Biosciences, Molecular and Environmental Toxicology Center, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States, ⁴Department of Population Health Sciences, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States.

Hypospadias, Intrauterine Growth Restriction, and Abnormalities of the Placenta
Toufaily MH¹, Roberts D², Westgate M-N¹, Hunt A-T³, Holmes LB¹. ¹MassGeneral Hospital for Children, Boston, MA, United States, ²Massachusetts General Hospital, Boston, MA, United States, ³Hunt Consulting Associates, Chapel Hill, NC, United States.

Changes in Serum Lipid Profiles in Neonatal Monkeys Associated with Sevoflurane-Induced Neurotoxicity
Slikker W¹, Wang C², Han X², Liu F¹, Gu Q¹, Liu S¹, Patterson T¹, Paule M¹, Hanig J³, Wang C¹. ¹National Center for Toxicological Research, US FDA, Jefferson, AR, United States, ²Center for Metabolic Origins of Disease, Sanford Burnham Prebys Medical Discovery Institute at Lake Nona, Orlando, FL, United States, ³Center for Drug Evaluation and Research, US FDA, Silver Spring, MD, United States.

Maternal Antihypertensive Medication Use and Selected Birth Defects in the National Birth Defects Prevention Study
Fisher SC¹, Van Zutphen AR^1,2, Werler MM³, Romitti PA⁴, Cunniff CM⁵. ¹Congenital Malformations Registry, New York State Department of Health, Albany, NY, United States, ²Department of Epidemiology and Biostatistics, School of Public Health, University at Albany, Rensselaer, NY, United States, ³Department of Epidemiology, School of Public Health, Boston University, Boston, MA, United States, ⁴Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA, United States, ⁵Department of Pediatrics, Weill Cornell Medical College, New York, NY, United States.

A Mysterious Story of Embryo-Foetal Developmental Toxicity in Rats with AX
Zhuang Q, Rasmussen AD, Bernholm K, Northeved H. Nonclinical Safety Research, H. Lundbeck A/S, Copenhagen, Denmark.

Birth Outcomes following Pregnancy Exposure to Adalimumab: The OTIS Autoimmune Diseases in Pregnancy Project
Chambers CD¹, Johnson DL¹, Xu R¹, Luo Y¹, Adam MP², Braddock SR³, Robinson L⁴, Vaux K¹, Jones KL¹, The OTIS Collaborative Research Group¹. ¹University of California–San Diego, La Jolla, CA, United States, ²University of Washington, Seattle, WA, United States, ³Saint Louis University, St. Louis, MO, United States, ⁴University at Buffalo, Buffalo, NY, United States.

Birth Defect Surveillance As a Requirement for Reducing Birth Defects in a Developing Country
Fakoya FA¹, Wade A². ¹St. George's University II, Newcastle Upon Tyne, United Kingdom, ²St. George's University, St. George's, Grenada.

Clinical Variability of the Congenital Zika Syndrome
Del Campo M¹, Feitosa IML², Garcia-Alix A³, Schuler-Faccini L². ¹University of California–San Diego, San Diego, CA, United States, ²Universidade Federal de Rio Grande do Sul, Porto Alegre, RGDS, Brazil, ³Institut de Recerca Pediatrica Hospital Sant Joan de Deu, Barcelona, Catalunya, Spain.