P15      Zika Related Birth Defect Surveillance in Missouri
Wambuguh L, Garrett L, Sapkota A, McCarthy E. Missouri Department of Health and Senior Services, Bureau of Vital Statistics, Jefferson City, MO, United States.

P16      An Evaluation of the New Zealand White Rabbit Model for Zika Virus Infection during Gestation and Microcephaly in the Offspring
O'Hara MF¹, Ramachandra R². ¹Covance Drug Development, Greenfield, IN, United States, ²Covance Immunology Services, Denver, PA, United States.

P17      Behavioral Screening of the LOPAC1280 Library Reveals that Zebrafish Embryos are Unable to Discriminate Modes of Action for Neuroactive Compounds
Vliet SM^1,2, Ho TC², Volz DC². ¹Environmental Toxicology Graduate Program, University of California–Riverside, Riverside, CA, United States, ²Department of Environmental Sciences, University of California–Riverside, Riverside, CA, United States.

P18      Evaluation of Maternal Transplacental Transfer of Anti-F-Antibodies to Pups Following Immunization of Pregnant Hartley Guinea Pigs with a Recombinant Respiratory Syncytial Virus Vaccine
Murphy CJ, Goodnight SY, Murphy L, Godin CS. Smithers Avanza, Gaithersburg, MD, United States.

P19      Maternal Diabetes Suppresses Mitochondrial Fusion Leading to Heart Defects through the miR-195-Mitofusin 1/Mitofusin 2 Circuit
Zhong J, Yang P. University of Maryland School of Medicine, Baltimore, MD, United States.

P20      The Development of Type 2 Diabetes in Nonobese Male Swiss-Webster Mice: Effect of Exposure to a Gluten-Free Diet
Kepko DS¹, Wells C¹, Boornazian A², Gosstola N², Smith H², Wing B², Munagala A², Thigpen H², Rasco JF², Bailey MM¹. ¹Emporia State University, Emporia, KS, United States, ²University of Alabama, Tuscaloosa, AL, United States.

P21      Survival of Infants with Spina Bifida and the Role of Maternal Pre-Pregnancy Body Mass Index
Pace ND¹, Siega-Riz AM¹, Olshan AF¹, Chescheir NC², Cole SR¹, Desrosier TA¹, Tinker SC³, Hoyt AT⁴, Canfield MA⁴, Carmichael SL⁵, Meyer RE⁶, The National Birth Defects Prevention Study³. ¹Department of Epidemiology, University of North Carolina–Chapel Hill, Chapel Hill, NC, United States, ²Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, University of North Carolina–Chapel Hill, Chapel Hill, NC, United States, ³National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA, United States, ⁴Birth Defects Epidemiology and Surveillance Branch, Texas Department of State Health Services, Austin, TX, United States, ⁵Department of Pediatrics, Division of Neonatology and Developmental Medicine, Stanford University School of Medicine, Stanford, CA, United States, ⁶Birth Defects Monitoring Program, North Carolina Department of Health and Human Services, Raleigh, NC, United States.

P22      Computational Toxicology and Computational Modeling of Embryonic Limb Development Using ToxCast High-Throughput Screening Data
Ahir B¹, Spencer R², Baker N², Judson R³, Martin M³, Knudsen T³. ¹University of Illinois College of Medicine at Chicago, Chicago, IL, United States, ²Lockheed Martin, US EPA, Research Triangle Park, NC, United States, ³National Center for Computational Toxicology, US EPA, Research Triangle Park, NC, United States.

P23      A 3D Organotypic Human Stem Cell Model to Evaluate Human Palatal Fusion
Wolf CJ, Belair DG, Becker CM, Abbott BD. US Environmental Protection Agency, Research Triangle Park, NC, United States.

P24      Assessment of Developmental Toxicity Potential of Glyphosate-Based Herbicides Using Drosophila melanogaster Primary Embryonic Stem Cell Cultures
Argueta JA, Torres A. California State University–San Bernardino, San Bernardino, CA, United States.

P25      Behavioral Profiling of Zebrafish Embryos Exposed to a Panel of Sixty Water-Soluble Compounds
Ali S¹, Champagne D², Richardson M². ¹Department of Zoology, The University of Azad Jammu and Kashmir, Muzaffarabad, Pakistan, ²Sylvius Laboratory, Institute of Biology, Leiden University, Leiden, The Netherlands.

P26      Teratological Effects of a Panel of Sixty Water-Soluble Toxicants on Zebrafish Development
Ali S¹, Aalders J², Richardson M². ¹Department of Zoology, The University of Azad Jammu and Kashmir, Muzaffarabad, Pakistan, ²Sylvius Laboratory, Institute of Biology, Leiden University, Leiden, The Netherlands.

P27      Developmental Toxicity of Leucomalachite Green on Zebrafish
Wan H, Zhang H. Guangdong Zhongke EnHealth Technology Co., Ltd., Foshan, China.

P28      Effect of Neonatal Abstinence Syndrome on Neurodevelopmental Outcomes at Six Months of Age in Infants Born to Women on Medication-Assisted Treatment for Opioid Use Disorder
Ashley M, Holbrook BD, Cano S, Lowe J, Stephen JM, Qeadan F, Leyva Y, Rayburn W, Leeman L, Bakhireva L. University of New Mexico Health Sciences Center, Albuquerque, NM, United States.

P29      Developmental Toxicity of Dimethadione and Acetylsalicylic Acid in Rats
Toy H¹, Harris SB², Mylchreest E¹. ¹Battelle, West Jefferson, OH, United States, ²Stephen B. Harris Group, San Diego, CA, United States.

P30      Exposure to QACs Alters Inflammatory Responses in Murine Macrophages
Nguyen HD¹, McDonald VA², Hrubec TC^1,3. ¹E. Via College of Osteopathic Medicine, VA Campus, Blacksburg, VA, United States, ²Department Biological Sciences, Virginia Tech, Blacksburg, VA, United States, ³VA-MD College of Veterinary Medicine, Blacksburg, VA, United States.

P31      Validation of and Disparities with Prevalence of Congenital Microcephaly: New York State 2013–2015
Fox D¹, Brady L¹, Pantea C¹, Graham K², Talati A², Browne M¹, Carter S³, Friedenberg E³, Vora N^3,4, Lee C^3,5. ¹Congenital Malformations Registry, New York State Department of Health, Albany, NY, United States, ²Public Health/Preventive Medicine Residency Program, New York City Department of Health and Mental Hygiene, New York City, NY, United States, ³Division of Disease Control, New York City Department of Health and Mental Hygiene, New York City, NY, United States, ⁴Office of Public Health Preparedness and Response, CDC, New York City, NY, United States, ⁵Epidemic Intelligence Service, CDC, New York City, NY, United States.

P32      Sex and Dose-Related Differences in Behavior Following Excess Taurine Consumption by B6 Mice during Adolescence and Early Adulthood
Villalona YE, Weimer JL, Massie LA, Marczinski CA, Curran CP. Northern Kentucky University, Highland Heights, KY, United States.

P33      From Inhibition of Retinoic Acid Catabolism to Facial Malformations: Suggestions for a New Adverse Outcome Pathway
Di Renzo F¹, Moretto A^1,2, Eberini I¹, Beronius A³, Zilliacus J³, Hanberg A³, Menegola E¹. ¹Università degli Studi di Milano, Milan, Italy, ²ICPS ASST Fatebenefratelli Sacco, Milan, Italy, ³Karolinska Instituted, Stockholm, Sweden.

P34      In Vitro Embryo Exposure to Retinoic Acid, Valproic Acid, Ethanol, and to the Antifungal Prochloraz Alone or in Mixture: Effects on Cranio-Facial Morphogenesis
Menegola E¹, Bacchetta R¹, Battistoni M¹, Di Renzo F¹, Metruccio F², Moretto A^1,2. ¹Università degli Studi di Milano, Milan, Italy, ²ICPS ASST Fatebenefratelli Sacco, Milan, Italy.

P35      Inflammogenic and Vascular Effects of Acute Pulmonary Exposure to Titanium Dioxide Nanoparticles
Abukabda AB, McBride CR, Nurkiewicz TR. West Virginia University, Morgantown, WV, United States.

P36      Battery of Reproductive Toxicology Studies Supporting the Safety of a Dopamine Receptor Antagonist, Molindone
Krishna G¹, Gopalakrishnan G¹, Yu C¹, Ganiger S², White T³. ¹Supernus Pharmaceuticals, Inc., Rockville, MD, United States, ²Advinus Therapeutics Ltd., Bengaluru, Karnataka, India, ³Aclairo Pharmaceutical Development Group, Inc., Vienna, VA, United States.

P37      Intersecting Principles of Teratology and Toxicology in Nursing Education and Community Engagement
Dodd-Butera T¹, Shaputnic C². ¹California State University, San Bernardino, CA, United States, ²University of California Institute for Fetal Alcohol Spectrum Disorders Discovery, San Diego, CA, United States.

P38      Effects of Quaternary Ammonium Compounds on Neural Stem/Progenitor Cells
Meade HA¹, Shea CS², Hrubec TC^2,3. ¹Department of Biochemistry, Virginia Tech, Blacksburg, VA, United States, ²E. Via College of Osteopathic Medicine, VA Campus, Blacksburg, VA, United States, ³VA-MD College of Veterinary Medicine, Virginia Tech, Blacksburg, VA, United States.

P39      Ontogeny of the Central Nervous System across Species
Williams AL¹, DeSesso JM^1,2. ¹Exponent, Inc., Alexandria, VA, United States, ²Georgetown University School of Medicine, Washington, DC, United States.

P40      Alcohol Exacerbates the Teratogenic Effects of Prenatal Cannabinoid Exposure in a C57BL/6J Mouse Model
Fish EW¹, Boschen KE¹, Murdaugh LB¹, Mendoza-Romero HN¹, Williams KP², Parnell SE¹. ¹University of North Carolina, Chapel Hill, NC, United States, ²North Carolina Central University, Durham, NC, United States.

P41      Evaluation of Ad Libitum Feeding in Pregnant Rabbits
Rayhon SL, Seethala RK, McNerney ME, Thompson KE. Bristol-Myers Squibb Company, New Brunswick, NJ, United States.

P42      Ocular Evaluations in Juvenile Dutch Belted Rabbits
Robinson KJ, Martin AI, Pouliot L, Vezina M. Charles River, Montréal, QC, Canada.

P43      Post Natal Cardiovascular Assessment in Juvenile Beagle Dogs Using Telemetry
Adamo M, Primakova I, Kirouac A, Norton K, Robinson K. Charles River, Montréal, QC, Canada.

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