| Sunday, June 25, 2017 |
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| 6:45 AM–7:45 AM |
STUDENT AFFAIRS COMMITTEE MEETING – Mt. Wilson |
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| 7:00 AM–6:00 PM |
REGISTRATION OPEN – Aspen Foyer |
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| 7:00 AM–6:00 PM |
SPEAKER READY ROOM OPEN – Crestone Peak |
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| 7:15 AM–7:45 AM |
MORNING COFFEE AND PASTRIES –Aspen Foyer |
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(Joint with DNTS) |
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| 7:45 AM–8:15 AM |
PRESIDENT'S WELCOME – Aspen Ballroom |
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Society for Birth Defects Research and Prevention President, Sonja A. Rasmussen, Centers for Disease Control and Prevention |
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| 8:15 AM–9:00 AM |
JOSEF WARKANY LECTURE – Aspen Ballroom |
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Eliminating Congenital Zika Syndrome: Lessons Learned from Rubella Elimination (L1) |
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(Joint with DNTS and OTIS) |
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Chairperson: Sonja A. Rasmussen, Centers for Disease Control and Prevention |
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Lecturer: José F. Cordero, University of Georgia |
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| 9:00 AM–10:00 AM |
THOMAS H. SHEPARD LECTURE – Aspen Ballroom |
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(Joint with OTIS) |
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From the FAS to OTIS: A Long Strange Trip |
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Chairperson: Stephen R. Braddock, Saint Louis University School of Medicine |
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Lecturer: Buzz Chernoff, California Environmental Protection Agency (Retired) |
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| 10:00 AM–10:30 AM |
SPOUSE AND GUEST MEET-AND-GREET – Mt. Wilson |
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(Open to Society for Birth Defects Research and Prevention, DNTS, and OTIS Spouses and Guests) |
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| 10:05 AM–1:00 PM |
GRADUATE STUDENT AND POSTDOCTORAL FELLOW PLATFORM SESSION 1 – Aspen Ballroom |
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Organized by the Student Affairs Committee |
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Chairperson: Dana L. Shuey, Incyte |
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| 10:05 AM-10:15 AM |
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Introduction |
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| 10:15 AM-10:30 AM |
1 |
Developmental Toxicity Testing of Cigarette Smoke and E-Cigarette Vapor Utilizing Drosophila melanogaster Primary Embryonic Stem Cell Cultures |
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Ubina TM, Juarez J, Gallardo M, Bournias-Vardiabasis N. California State University–San Bernardino, San Bernardino, CA, United States. |
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| 10:30 AM-10:45 AM |
2 |
Oxidative Stress-Induced Harm Reduction Tobacco Products Misregulates the Development of Bone |
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Sparks NRL, Walker LM, Sera S, zur Nieden NI. University of California–Riverside, Riverside, CA, United States. |
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| 10:45 AM-11:00 AM |
3 |
Genetic Screening for Ethanol-Sensitive Zebrafish Mutants Identifies a Requirement for Bmp Signaling in Endoderm and Jaw Development |
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Lovely CB, Swartz ME, McCarthy N, Norrie JL, Henegar T, Eberhart JE. University of Texas–Austin, Austin, TX, United States. |
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| 11:00 AM-11:15 AM |
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Break-Aspen Foyer |
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| 11:15 AM-11:30 AM |
4 |
Harm-Reduction Tobacco Products Deleteriously Alter AKT and Other Survival-Related Signaling Pathways during Normal Embryonic Osteogenesis |
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Walker LM, Sparks NRL, zur Nieden NI. University of California-Riverside, Riverside, CA, United States. |
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| 11:30 AM-11:45 AM |
5 |
Changes to Primary Cilia Number and Function in the Neural Tube Following Neurulation-Stage Ethanol Exposure in a Mouse Model of FASD
Boschen KE, Fish EW, van Venrooy AI, Parnell SE. University of North Carolina, Chapel Hill, NC, United States. |
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| 11:45 AM-12:00 Noon |
6 |
Complex Mixtures of Anti-Androgens at Concentrations below Individual Chemical Effect Levels Produces Reproductive Tract Malformations in the Male Rat
Conley JM1, Lambright CR1, Evans N1, Cardon MC1, Medlock-Kakaley E1,2, Wilson VS1, Gray LE1. 1US EPA/ORD/NHEERL/TAD/RTB, Research Triangle Park, NC, United States, 2US EPA-UNC Cooperative Toxicology Program, Research Triangle Park, NC, United States. |
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| 12:00 Noon-12:15 PM |
7 |
Folic Acid As a Radioprotectant: Efficacy in Preventing X-Ray Induced Congenital Malformations
Craenen K1,2, Verslegers M1, Craeghs L1,2, Buset J1, Neefs M1, Baatout S1, Moons L2, Benotmane MA1. 1Radiobiology Unit, SCK-CEN, Mol, Belgium, 2Neural Circuit Development and Regeneration Research Group, KUL, Leuven, Belgium. |
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| 12:15 PM-12:30 PM |
8 |
Effect of Maternal Depression and Prenatal Antidepressant Exposure on Placental Serotoninergic and Glucocorticoids Systems Methylation
Laurent L1, Peñaherrera M2,3, Robinson WP2,3, Oberlander TF2,3, Vaillancourt C1. 1INRS-Institut Armand Frappier, Laval, QC, Canada, 2BC Children's Hospital Research Institute, Vancouver, BC, Canada, 3University of British Columbia, Vancouver, BC, Canada. |
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| 12:30 PM-12:45 PM |
9 |
Regional Differences and Correlates of Prevalence of Prenatal Alcohol Exposure in Texas As Assessed by PEth in Newborn Dry Blood Spots
Shrestha S1, Williams S1, Miranda R2, Bakhireva L1. 1University of New Mexico, Albuquerque, NM, United States, 2Texas A&M Health Science Center, College of Medicine, Bryan, TX, United States. |
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| 12:45 PM-1:00 PM |
10 |
Genomic Variations in Ebstein Anomaly and Cardiomyocyte Differentiation
Giannakou AG1, Sicko SRJ2, Kay KDM2, Fan FR5, Jelliffe-Pawlowski PLL3, Shaw SG4, Mills JLM1. 1National Institutes of Health, NICHD, DIPHR, Bethesda, MD, United States, 2Wadsworth Center, NYSDOH, Albany, NY, United States, 3University of California–San Francisco, School of Medicine, San Francisco, CA, United States, 4Stanford School of Medicine, Stanford, CA, United States, Georgetown University, Washington, DC, United States. |
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| 1:00 PM–2:00 PM |
LUNCH ON YOUR OWN |
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| 1:00 PM–2:00 PM |
GRADUATE STUDENT AND POSTDOCTORAL FELLOW PROFESSIONAL
DEVELOPMENT WORKSHOP – Mt. Columbia
Effective Communication: Platforms, Posters,
and Professional Settings
(Advance Registration Required) |
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Chairperson: Dinesh J. Stanislaus, GlaxoSmithKline |
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| 1:00 PM–1:05 PM |
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Introduction |
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Dinesh J. Stanislaus, GlaxoSmithKline |
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| 1:05 PM–1:20 PM |
W1 |
Effective Platform Presentations: Do’s and Don’ts |
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Nicole Churchill Kleinstreuer, NTP Interagency Center for the Evaluation of Alternative Toxicological Methods, NIEHS |
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| 1:20 PM–1:35 PM |
W2 |
Effective Posters: Do’s and Don’ts |
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Kary E. Thompson, Bristol-Myers Squibb |
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| 1:35 PM–2:00 PM |
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Discussion About Professional Settings Interactions |
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| 2:00 PM–2:30 PM |
F. CLARKE FRASER NEW INVESTIGATOR AWARD – Aspen Ballroom |
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Antibody Therapeutics: Structure, Function, and Placental Transfer |
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Chairperson: Janee Gelineau-van Waes, Creighton University School of Medicine |
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Lecturer: Evi Struble, US Food and Drug Administration |
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| 2:30 PM–3:00 PM |
JAMES G. WILSON PUBLICATION AWARD – Aspen Ballroom |
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A 2015 global update on folic acid-preventable spina bifida and anencephaly |
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Chairperson: Norbert Makori, Charles River |
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Lecturer: Vjaya Kancherla, Emory University |
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| 3:00 PM–3:30 PM |
PATRICIA RODIER MID-CAREER AWARD FOR RESEARCH AND MENTORING – Aspen Ballroom |
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Project Newborn: What We Have Learned from 20 Years of Research on Prenatal Cocaine Exposure? |
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(Joint with DNTS) |
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Chairperson: Janee Gelineau-van Waes, Creighton University School of Medicine and Patricia A. Janulewicz Lloyd, Boston University School of Public Health |
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Lecturer: Sonia Minnes, Case Western Reserve University |
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| 3:35 PM–6:30 PM |
WILEY-BLACKWELL SYMPOSIUM
Developmental Metabolism: Consequences to and from Neural Lineages – Aspen Ballroom |
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Chairpersons and Scientific Liaison Coalition Representatives: Thomas B. Knudsen, National Center for Computational Toxicology, US EPA and Mary Alice Smith, University of Georgia |
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| 3:35 PM–3:50 PM |
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Introduction |
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| 3:50 PM–4:25 PM |
S1 |
Molecular Pathology of Neural Tube Defects in Diabetic Pregnancies |
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J. Michael Salbaum, Pennington Biomedical Research Center, LSU |
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| 4:25 PM-4:40 PM |
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Break - Aspen Foyer |
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| 4:40 PM–5:15 PM |
S2 |
Apoptotic Mechanism of Maternal Diabetes-Induced Neural Tube Defects |
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Peixin Yang, University of Maryland–Baltimore |
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| 5:15 PM–5:50 PM |
S3 |
Development of Neuroendocrine Systems Governing Energy Homeostasis |
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Chen Liu, UT Southwestern University |
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| 5:50 PM–6:25 PM |
S4 |
Modeling of Developmental Neurotoxicity Using Pluripotent Stem Cell-Derived Neurons and Astrocytes is Generating New Mechanistic Insights |
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Steve Stice, University of Georgia |
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| 6:25 PM–6:30 PM |
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Closing Remarks |
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| 3:35 PM–6:30 PM |
PREGNANCY REGISTRY UPDATES SYMPOSIUM (Joint with OTIS) – Colorado Ballroom A |
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Chairpersons: Christina D. Chambers, University of California-San Diego and Lewis B. Holmes, MassGeneral Hospital for Children |
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| 3:35 PM–3:40 PM |
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Welcome and Introduction |
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Lewis B. Holmes, MassGeneral Hospital for Children |
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| 3:40 PM–4:00 PM |
S5 |
The Key Role of Social Media in Registry Recruitment |
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Nicole Chavez, Communications Consultant |
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| 4:00 PM–4:20 PM |
S6 |
"Drugs in Breast Milk": Related Data in Pregnancy Registries |
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Shinya Ito, The Hospital for Sick Children |
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| 4:20 PM–4:35 PM |
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Break - Aspen Foyer |
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| 4:35 PM–4:55 PM |
S7 |
How to Interpret Different Findings for the Same Medication Across Pregnancy Registries: The Example of Keppra |
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David Miller, UCB Biosciences, Inc |
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| 4:55 PM–5:15 PM |
S8 |
Incorporating Registry Data into the Label—Guidance for the PLRR |
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Leyla Sahin, US Food and Drug Administration |
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| 5:15 PM–5:30 PM |
S9 |
Defect Evaluation by Infant Photographs in a Multi-Center Pharmaceutical Clinical Trial
Scheuerle AE1, Kwon P2, Joing M2. 1University of Texas Southwestern Medical Center, Dallas, TX, United States, 2NORA Therapeutics, Inc., Palo Alto, CA, United States. |
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| 5:30 PM–5:45 PM |
S11 |
Distribution by Week and Trimester of Onset among Pregnant Women, US Zika Pregnancy Registry, 2015–2016
Khan S1, Rice ME1, Reynolds MR1, Reagan-Steiner S1, Brown CM5, Lee EH4, Ahmad N2, Macdonald J3, Sommer JN2, Smith LC2, Honein MA1. 1Centers for Disease Control and Prevention, Atlanta, GA, United States, 2New York State Department of Health, Albany, NY, United States, 3Virginia Department of Health, Richmond, VA, United States, 4New York City Department of Health and Mental Hygiene, Queens, NY, United States, 5Massachusetts Department of Public Health, Boston, MA, United States. |
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| 5:45 PM–6:00 PM |
S10 |
Prevalence of Small for Gestational Age and Preterm Birth Among Infants Born to Women with Laboratory Evidence of Possible Zika Virus Infection During Pregnancy, US Zika Pregnancy Registry, December 2015–December 2016
Fleck-Derderian S1, Jones AM1, Simon EL1, Newsome K1, Lee EH2, Ahmad N3, Dunn JE4, Smith LC3, White JL3, Honein MA1. 1Centers for Disease Control and Prevention, Atlanta, GA, United States, 2New York City Department of Health and Mental Hygiene, New York City, NY, United States, 3New York State Department of Health, Albany, NY, United States, 4Massachusetts Department of Public Health, Boston, MA, United States. |
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| 6:00 PM–6:15 PM |
S12 |
Pregnancy and Lactation Labeling Rule (PLLR) in Practice: More Human Observational Data Needed
Wurst KE1, Cunnington M3, Powell M2, Lee TJ1. 1GlaxoSmithKline, Collegeville, PA, United States, 2GlaxoSmithKline, Research Triangle Park, NC, United States, 3GlaxoSmithKline, Stevenage, United Kingdom. |
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| 6:15 PM–6:30 PM |
S13 |
Lactation Study Challenges and Solutions
Hurst N1, Covington D2. 1PPD, Inc., Morrisville, NC, United States, 2Evidera, Wilmington, NC, United States. |
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| 6:35 PM–7:00 PM |
CELEBRATING THE LIFE OF THOMAS H. SHEPARD – Aspen Ballroom |
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(Joint with OTIS) |
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Chairpersons: Sonja A. Rasmussen, Centers for Disease Control and Prevention and Stephen R. Braddock, Saint Louis University School of Medicine |
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Speakers: Elaine M. Faustman, University of Washington (S14) and
Godfrey P. Oakley Jr., Emory University (S15) |
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| 7:00 PM–8:30 PM |
WELCOME RECEPTION, GRADUATE STUDENT AND POSTDOCTORAL FELLOW RESEARCH SHOWCASE, AND EXHIBITS ATTENDED – Capitol Peak A
(Joint with DNTS) |
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| 8:30 PM–9:00 PM |
NEW MEMBER "SUNDAE" NIGHT SOCIAL - Crystal Peak C |
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(By Invitation Only) |
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| 8:30 PM–9:30 PM |
PUBLICATIONS COMMITTEE MEETING - Mt. Princeton |
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