Program
Meeting Agenda
Society for Birth Defects Research and Prevention 2022 Annual Meeting—From Bench to Bedside and Back Again
Please note that The times listed are in PDT – Pacific Daylight Time (US).
P1
Christensen
K1, Lehmann G2, Meeker J3,
Yost EE2. 1US Environmental Protection Agency, Washington,
DC, United States, 2US Environmental Protection Agency, Research Triangle
Park, NC, United States, 3University of Michigan, School of Public Health,
Ann Arbor, MI, United States. Considerations for the Critical Appraisal of Epidemiology
Studies on the Developmental Toxicity of PCBs
P2
Martin-Giacalone
BA1, Lin AE2, Kirby RS3, Nestoridi
E4, Liberman RF4, Rasmussen SA5,6, Nembhard WN7,
Agopian AJ8, Carey JC9, Cragan JD10, Leedom V6,
Nance A11, Piccardi M12, Sandidge T13, Shan X14,
Shumate C15, Stallings EB10, Stevenson R16, Lupo PJ1. 1Baylor College of Medicine, Houston, TX, United
States, 2Massachusetts General Hospital for Children, Boston, MA, United
States, 3University of South Florida, Tampa, FL, United States, 4Massachusetts
Department of Public Health, Boston, MA, United States, 5University of
Florida College of Medicine, Gainesville, FL, United States, 6South Carolina
Department of Health and Environmental Control, Columbia, SC, United States, 7University
of Arkansas for Medical Sciences, Little Rock, AR, United States, 8University
of Texas Health Science Center School of Public Health, Houston, TX, United States,
9University of Utah Health, Salt Lake City, UT, United States, 10National
Center on Birth Defects and Developmental Disabilities, Centers for Disease Control
and Prevention, Atlanta, GA, United States, 11Utah Department of Health,
Salt Lake City, UT, United States, 12Maryland Department of Health, Baltimore,
MD, United States, 13Illinois Department of Public Health, Springfield,
IL, United States, 14Arkansas Children's Research Institute, Little Rock,
AR, United States, 15Texas Department of State Health Services, Austin,
TX, United States, 16Greenwood Genetic Center, Greenwood, SC, United
States. Prevalence and Descriptive Epidemiology of Turner Syndrome in
the United States: A Report from the National Birth Defects Prevention Network (NBDPN)
P3
Fisher
SC1, Howley MM1, Tran EL2,3,
Ailes EC3, Papadopoulos EA1, Nembhard WN4, Browne
ML1,5. 1Birth Defects Registry, New York State Department
of Health, Albany, NY, United States, 2Eagle Global Scientific LLC, San
Antonio, TX, United States, 3Division of Birth Defects and Infant Disorders,
National Center on Birth Defects and Developmental Disabilities, Centers for Disease
Control and Prevention, Atlanta, GA, United States, 4Department of Epidemiology,
University of Arkansas for Medical Sciences, Little Rock, AR, United States, 5Department
of Epidemiology and Biostatistics, School of Public Health, University at Albany,
Rensselaer, NY, United States. Maternal
Cyclobenzaprine Exposure and Risk of Birth Defects in the National Birth Defects
Prevention Study (1997–2011) and Birth Defects Study to Evaluate Pregnancy
Exposures (2014–2018)
P4
Bedard
T1, Thomas MA2, Lowry RB2,
Grevers X1, Crawford S3. 1The Alberta Congenital Anomalies Surveillance System, Clinical Genetics,
Alberta Children's Hospital, Calgary, AB, Canada, 2Department of Medical
Genetics, University of Calgary, Alberta Children's Hospital, Calgary, AB, Canada,
3Alberta Perinatal Health Program, Alberta Health Services, Calgary,
AB, Canada. Descriptive Epidemiology
of 63 Cases with Oculo-Auriculo-Vertebral Spectrum, from the Alberta Congenital
Anomalies Surveillance System, 1997–2019
P5
Woodhouse
JP1, Benjamin RH2, Agopian AJ2, Langlois PH3,
Canfield MA4, Lupo PJ1, Schraw JM1. 1Pediatrics, Baylor College of Medicine, Houston, TX, United States, 2UTHealth
School of Public Health, Houston, TX, United States, 3University of Texas
UTHealth School of Public Health, Austin, TX, United States, 4Texas Department
of State Health Services, Birth Defects Epidemiology and Surveillance Branch, Austin,
TX, United States. Parental and Infant Factors Associated with Nonsyndromic
Anotia-Microtia, Texas, 1999–2014
P6
Shumate
C1, Agopian AJ2, Salemi J3,
Le M1, Arena F1, Canfield MA1. 1Birth Defects Epidemiology and Surveillance Branch, Texas Department of
State Health and Human Services, Austin, TX, United States, 2Division
of Epidemiology, Human Genetics and Environmental Sciences, University of Texas
School of Public Health, Houston, TX, United States, 3University of South
Florida College of Public Health, Tampa, FL, United States. The Contribution
of Outpatient Hospital Discharge Data for Hypospadias Case Finding and Completeness
P7
Betancourt
D, Canfield MA, Kubenka C, Childers-Dykes
A, Shumate C, Drummond-Borg M. Texas
Department of State Health Services, Birth Defects Epidemiology and Surveillance
Branch, Austin, TX, United States. Pilot to Refer Older Children from
the Texas Birth Defects Registry to Agency Social Workers for Assistance in Accessing
Health and Social Services
P8
Goodman
CV1, Till C1, Arbuckle T2, Green
R1, Hornung R3, Lanphear B4, Séguin J5,
Booij L5, Fisher M2, Muckle G6, Bouchard M5,
Ashley-Martin J2. 1York University, Toronto, ON, Canada, 2Health
Canada, Ottawa, ON, Canada, 3Cincinnati Children's Hospital Medical Center
(Retired), Cincinnati, OH, United States, 4Simon Fraser University, Vancouver,
BC, Canada, 5University of Montreal, Montreal, QB, Canada, 6Laval
University, Quebec City, QB, Canada. Prenatal PFAS Exposure and IQ in
Preschool-Aged Canadian Children: The MIREC Cohort
P9
Aboulatta
L1, Kowalec K1,2, Leong C1,3,
Delaney J1,4, Falk J1, Alessi-Severini S1,5, Eltonsy
S1,6. 1College of Pharmacy, Rady Faculty of Health Sciences,
University of Manitoba, Winnipeg, MB, Canada, 2Department of Medical
Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden, 3Department
of Psychiatry, College of Medicine, Rady Faculty of Health Sciences, University
of Manitoba, Winnipeg, MB, Canada, 4Department of Epidemiology, University
of Washington, Seattle,
WA, United States, 5Manitoba
Centre for Health Policy, Winnipeg, MB, Canada, 6The Children's Hospital
Research Institute of Manitoba, Winnipeg, MB, Canada. Impact of COVID-19
Pandemic on Preterm Birth and Stillbirth Rates in Manitoba, Canada: A Quasi-Experimental
Study
P10
Desrochers
B, Lavu A, Valencia E, Vaccaro C, Eltonsy
S. College of Pharmacy, University
of Manitoba, Winnipeg, MB, Canada. Adverse Fetal Outcomes Associated with
Gabapentin Use in Pregnancy: A Cohort Study and Meta-Analysis
P11
Abstract Withdrawn
P12
Kancherla
V1, Wagh K1, Priyadarshini P2,
Pachón H2,3, Oakley Jr. GP1. 1Center for Spina Bifida Prevention, Department of Epidemiology, Emory University
Rollins School of Public Health University, Atlanta, GA, United States, 2Hubert
Department of Global Health, Rollins School of Public Health, Emory University,
Atlanta, GA, United States, 3Food Fortification Initiative, Atlanta,
GA, United States. The Global Status of Folic Acid-Preventable Spina
Bifida and Anencephaly in the Year 2020: 30-Year Anniversary of Gaining
Knowledge about Folic Acid’s Prevention Potential for Neural Tube Defects
P13
Liang
H-W1, Greenald D2, Birru R1,
Zhao Y3, Koistinen H4, Mitchell R5, Xun X1,
Wang J6, Snyder N7, Barrett E8, O’Connor T9,
Miller R10, Simhan H11, Adibi JJ1. 1Department of Epidemiology, Graduate School of Public Health, University
of Pittsburgh, Pittsburgh, PA, United States, 2Centre for Reproductive
Health, University of Edinburgh, South Bridge, United Kingdom, 3St. Jude
Children's Research Hospital, Pittsburgh, PA, United States, 4HUSLAB,
Helsinki University Hospital, Helsinki, Finland, 5Developmental Endocrinology,
The University of Edinburgh, South Bridge, United Kingdom, 6Department
of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh,
PA, United States, 7Lewis Katz School of Medicine at Temple University,
Philadelphia, PA, United States, 8Department of Biostatistics and Epidemiology,
Rutgers-School of Public Health, Piscataway, NJ, United States, 9Psychiatry,
University of Rochester, Rochester, NY, United States, 10School of Medicine
and Dentistry, University of Rochester Medical Center, Rochester, NY, United States,
11Magee-Womens Research Institute, Pittsburgh, PA, United States. Evaluation
of the Fetal Sex-Specific Effects of Mono-N-Butyl and Monobenzyl Phthalate on
Placental Gene Expression in the First Trimester
P14
Ortiz-Newmark
AM1, Rueda-Esteban RJ1, Sarmiento LA1,2.
1Universidad de los Andes School of Medicine,
Bogota, Colombia, 2Gynecology Department Fundacion Santa Fe de Bogota,
Bogota, Colombia. Sirenomelia, Cervical Myelomeningocele, and Meromelia:
An Unusual Association—Case
Report and Literature Review
P15
Lu
L, Yuan F, Liu J, Chen S-Y. Department of Pharmacology and Toxicology, Alcohol
Research Center, University of Louisville Health Science Center, Louisville, KY,
United States. Exposure of Human Forebrain Organoids to Ethanol Disrupted
the Formation of Radial Glial Processes and Impaired the Generation, Migration,
and Transformation of Outer Radial Glia Cells
P16
Wiegand
JL, Cheng V, Reddam A, Avila-Barnard
S, Volz D. University of California,
Riverside, Riverside, CA, United States. Triphenyl Phosphate-Induced
Pericardial Edema Is Associated with Elevated Epidermal Ionocytes within
Zebrafish Embryos
P17
Dickson
S, Waddell M, Zablocki V, Bailey
B, Dodge P, Kopkau H, Nadolski K. Central
Michigan University College of Medicine, Mount Pleasant, MI, United States. In
Utero Effects of Opioids on Fetal Growth
Kumar
SN1, Bastia B1, Deval R2, Bhardwaj
SK3, Kumar N1, Borgohain D4, Akhtar N1,
Raisuddin S5, Kumar
Jain A1. 1Environmental Toxicology Lab, ICMR-NIP, New Delhi,
India, 2Department of Biotechnology, IIET, Inverstis University, Bareilly,
UP, Bareilly, India, 3Shimadzu Analytical India Pvt Ltd, DELHI, India,
4Assam Medical College, Dibrugarh, Assam, Dibrugarh, India, 5Department
of Medical Elementology and Toxicology, Jamia Hamdard, DELHI, India. Organochlorine
Pesticides Induce Oxidative Stress and DNA Damage in Tea Plantation Workers and
Their Correlation with Fetal Growth Restrictions
P19
Ruden
X1, Abdulhasan M2, Puscheck EE1, Ruden D1,
Rappolee DA1. 1Wayne State University,
Detroit, MI, United States, 2Reproductive Stress; Measurement, Mechanisms
and Management S Corp., Grosse Pointe Farms, MI, United States. The Earliest Embryonic Stem Cell Lineage of the Blastocyst Has Two Fates and Some Toxicants Drive Fate One and Suppress Fate Two, While Others Drive Towards Fate Two
P20
Olufosoye
O, Subramaniam S, Bailey B.
Central Michigan University, College of
Medicine, Mount Pleasant, MI, United States. Impact of In Utero Opioid Exposure on Developmental
Delays and Growth at 12 Months of Age
P21
Memon
S1, Singha S2, Memon F3, Isaac
AD1. 1Liaquat University of Medical and Health Sciences,
Jamshoro, Pakistan, 2Isra University, Hyderabad, Pakistan, 3Altamash,
Hospital, Karachi, Pakistan. Autism-Like Behavior and Astrocytic
Changes Associated with Autism as Consequence of Pre and Postnatal Exposure to
Bisphenol A in Wistar Albino Rat Offspring
P22
Kaldhone
PR1, Bryant M2, Sepehr E3, He
X2, Felton R2, LeeG4, Mellon RD4, Fisher
JE4, Hanig J4, Beger RD2, Inselman AL2.
1FDA/ NCTR, Jefferson, AR, United States, 2FDA/NCTR,
Jefferson, AR, United States, 3FDA/NCTR/CBER, Jefferson/Laurel, AR, United
States, 4FDA/CDER, Silver Spring, MD, United States. Developmental
Toxicity from Gestational Opioid Exposure in a CF-1 Mouse Model
P23
Green
R1, Goodman CV1, Flora D1,
Lanphear B2, Cill C1. 1York University, Toronto, ON, Canada, 2Simon Fraser University,
Vancouver, BC, Canada. Comparison of the Associations between
Prenatal Fluoride, Lead and Perfluoroalkyl Substances, and Boys IQ Scores in
the MIREC Cohort
P24
Jamalpoor
A, Hartvelt S, Flatt L, Zwetsloot
T, Feliksik M, Osterlund T, Hendriks G. Toxys B.V., Oegstgeest, The Netherlands. ReproTracker: A
Human Stem Cell-Based Biomarker Assay for In
Vitro Assessment of Developmental Toxicity
P25
Kagan
MS1, Zurakowski D1,2, Mongerson C1,
Jennings RW2,3,4, Bajic D1,2. 1Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children’s
Hospital, Boston, MA, United States, 2Harvard Medical School, Boston,
MA, United States, 3Department of Surgery, Boston Children’s Hospital,
Boston, MA, United States, 4Esophageal and Airway Treatment Center, Boston
Children’s Hospital, Boston, MA, United States. Mammillary Body
Quantification in a Pilot Cohort of Critically Ill Infants
P26
Hall
M1, Green R1, Goodman CV1,
Lanphear B2, Till C1. 1Department of Psychology,
Faculty of Health, York University, Toronto, ON, Canada, 2Faculty of
Health Sciences, Simon Fraser University, Burnaby, BC, Canada. Maternal
Hypothyroidism in Pregnancy is Associated with Lower IQ in Boys, but not Girls
P27
Gallego
MP, Irijalba I, Quevedo C, Muriana A, Weiner A. BBD BioPhenix SL-Biobide, Donostia-San Sebastián,
Spain. Validation of Zebrafish Embryotoxicity Test (ZET) as a
Qualified Alternative Assay for its Regulatory Use
P28
Palmer
JA, Donley EL, Burrier RE. Stemina Biomarker Discovery, Inc., Madison, WI, United
States. devTOX quickPredict
Accurately Predicts the Developmental Toxicity Potential of the ICH S5(R3)
Guideline Reference Compounds
P29
Curran
CP, Clough K, Foster E, Kyntchev
A, Berling K, Perry C, Towell A, Feltner M, Honaker A, Creech H. Northern Kentucky University, Highland Heights,
KY, United States. Biochemical and Microbiome Changes in Cyp1a1 Knockout and Wild Type Mice
Following Developmental Exposure to benzo[a]pyrene
P30
Kula
J, Davis D, Hrubec TC.
Virginia College of Osteopathic Medicine,
Blacksburg, VA, United States. Do Cytokine Profiles in Maternal Mouse
Macrophages and Placental Tissue Influence the Formation of Neural Tube Defects
in QAC Exposed Mice
P31
Sok
P1, Sabo A2, Almli LM3, Jenkins
MM3, Nembhard WN4, Agopian AJ5, Bamshad MJ6,7,
Blue EE7,8, Brody LC9, Brown AL1, Browne ML10,11,
Canfield MA12, Carmichael SL13, Chong JX6,7, Feldkamp
ML14, Finnell RH15, Gibbs R2, Kay DM16,
Lei Y15, Moore CA3, Mullikin JC9, Muzny D2,
Olshan AF17, Pangilinan F9, Reefhuis J3, Romitti
PA18, Schraw JM1, Shaw GM13, Werler MM19,
Harpavat S20, Lupo PJ1. 1Pediatrics, Baylor College of Medicine, Houston, TX, United States, 2Human
Genome Sequencing Center, Baylor College of Medicine, Houston, TX, United States,
3Centers for Disease Control and Prevention, Atlanta, GA, United
States, 4Fay W. Boozman College of Public Health, University of Arkansas
for Medical Sciences, Little Rock, AR, United States, 5Department of
Epidemiology, Human Genetics, and Environmental Sciences, University of Texas School
of Public Health, Houston, TX, United States, 6Division of Genetic Medicine,
Department of Pediatrics, University of Washington, Seattle, WA, United States,
7Brotman Baty Institute for Precision Medicine, Seattle, WA, United States,
8Division of Medical Genetics, Department of Medicine, University of
Washington, Seattle, WA, United States, 9Genetics and Environment Interaction
Section, National Human Genome Research Institute, National Institutes of Health,
Bethesda, MD, United States, 10Birth Defects Registry, New York State
Department of Health, Albany, NY, United States, 11Department of Epidemiology
and Biostatistics, School of Public Health, University at Albany, Rensselaer, NY,
United States, 12Texas Department of State Health Services, Austin, TX,
United States, 13Stanford University School of Medicine, Stanford,
CA, United States, 14University of Utah School of Medicine, Salt Lake
City, UT, United States, 15Center for Precision Environmental Health,
Baylor College of Medicine, Houston, TX, United States, 16Division of
Genetics, Wadsworth Center, New York State Department of Health, Albany, NY, United
States, 17University of North Carolina, Chapel Hill, NC, United States,
18University of Iowa, Iowa City, IA, United States, 19Boston
University, Boston, MA, United States, 20Gastroenterology, Hepatology
and Nutrition, Texas Children’s Hospital, Houston, TX, United States. Exome-Wide
Assessment of Isolated Biliary Atresia: Using Child-Parent Trios and a
Case-Control Design to Identify Novel Rare Variants
P32
Yost
EE1, Chiang C1, Keating AF2,
Christensen K3, Lehmann G1. 1US EPA, Research Triangle Park, NC, United States, 2Iowa State
University, Ames, IA, United States, 3US EPA, Washington, DC, United
States. Considerations for the Critical Appraisal of Animal
Toxicology Studies on the Developmental Toxicity of PCBs
P33
Peymani
P1, Winquist B2,3, Shouman W1,
Lavu A1, Delaney J1, Kowalec K1, Ng M4,
Eltonsy S1,5. 1College of Pharmacy, Rady Faculty of Health Sciences,
University of Manitoba, Winnipeg, MB, Canada, 2College of Medicine, University
of Saskatchewan, Saskatoon, SA, Canada, 3Saskatchewan Health Quality
Council, Saskatoon, SK, Canada, 4Section of Neurology, University of
Manitoba, Winnipeg, MB, Canada, 5The Children’s Hospital Research Institute
of Manitoba, Winnipeg, MB, Canada. Trend Analysis of the
Antiepileptic Drugs Utilization in Pregnant Women with Epilepsy in Canada
P34
Shan
X1, Aguilar S2, Canon S1. 1Arkansas Children's Research Institute, Little Rock, AR, United States,
2University of Arkansas for Medical Sciences, Little Rock, AR, United
States. Prevalence of Hypospadias by Degree of Severity and
Associated Risk Factors
P35
Goli
K1, Mimi Le2, Langlois PH3, Canfield MA2,
Lupo PJ1, Schraw JM1. 1Baylor College of Medicine, Houston, TX, United States, 2Texas
Department of State Health Services, Birth Defects Epidemiology and Surveillance
Branch, Austin, TX, United States, 3University of Texas UTHealth School
of Public Health, Austin, TX, United States. Maternal Hypertension
and Structural Birth Defects: A Phenome-Wide Association Study
P36
Musfee
FI1, Politis M1,2, Cen R1, Magann
EF3,4, Nembhard WN3,5. 1Arkansas Center for Birth Defects Research and Prevention, Fay W. Boozman
College of Public Health, University of Arkansas for Medical Sciences, Little Rock,
AR, United States, 2Department of Environmental Medicine and Public Health,
Icahn School of Medicine at Mount Sinai, New York, NY, United States, 3Arkansas
Center for Birth Defects Research and Prevention, Fay W. Boozman College of Public
Health, University of Arkansas for Medical Sciences, Little Rock, AR, United States,
4Department of Maternal Fetal Medicine, University of Arkansas for Medical
Sciences, Little Rock, AR, United States, 5Department of Epidemiology,
Fay W Boozman College of Public Health, University of Arkansas for Medical Sciences,
Little Rock, AR, United States. Neighborhood Deprivation during
Pregnancy and Risk of Stillbirths
P37
Bedard
T1, Thomas MA2, Lowry RB2,
Grevers X1, Crawford S3. 1The Alberta Congenital Anomalies Surveillance System, Clinical Genetics,
Alberta Children's Hospital, Calgary, AB, Canada, 2Department of Medical
Genetics, University of Calgary, Alberta Children's Hospital, Calgary, AB, Canada,
3Alberta Perinatal Health Program, Alberta Health Services, Calgary,
AB, Canada. The Oculo-Auriculo-Vertebral Spectrum and Associated
Congenital Anomalies in 63 Cases from the Alberta Congenital Anomalies
Surveillance System, 1997–2019
P38
Wartko
PD1, Singh U1, Howe A2, Shortreed
SM1, D'Souza S3, Fuller S1, Mangione-Smith RM1,
Dublin S1. 1Kaiser Permanente Washington Health Research
Institute, Seattle, WA, United States, 2School of Medicine, University
of Auckland, Auckland, New Zealand, 3School of Social Sciences, University
of Auckland, Auckland, New Zealand. Trends in Antiemetic Medication
Use in Pregnancy in an Integrated Health System in the US, 2010–2021
P39
Shumate
C1, Navarro L1, Howell R1,
Agopian AJ2, Canfield MA1. 1Birth Defects Epidemiology and Surveillance Branch, Texas Department of
State Health and Human Services, Austin, TX, United States, 2Division
of Epidemiology, Human Genetics and Environmental Sciences, The University of Texas
School of Public Health, Houston, TX, United States. Predicting
Four-Year Mortality Among Infants with Birth Defects Using Two Comorbidity
Indices: The Pediatric Medical Complexity Algorithm and the Charlson
Comorbidity Index, Texas, 2010–2014
P40
Betancourt
D1, Canfield MA1, Kubenka C1,
Ethen M1, Shumate C1, Palacios J2. 1Texas Department of State Health Services, Birth Defects Epidemiology and
Surveillance Branch, Austin, TX, United States, 2Harris Health System,
Houston, TX, United States. Collaboration Between the Texas Birth
Defects Registry and Social Workers to Connect Children with Birth Defects to
Health and Social Service Programs
P41
Nava
de Escalante Y1, Abayomi A1, Langlois S2,3,
Xibiao Ye1,4, Erickson A1, Ngo H1, Armour R5,
Arbour L3,6, Bedard T7, Der K2, Van Allen M3,
Skarsgard E8,9, Lavoie M10, Henry B11. 1Office of Provincial Health Officer, Victoria, BC, Canada, 2Perinatal
Services British Columbia, Vancouver, BC, Canada, 3Department of Medical
Genetics, University of British Columbia, Vancouver, BC, Canada, 4Health
Information Science, University of Victoria, Victoria, BC, Canada, 5Vital
Statistics Agency (retired), Victoria, BC, Canada, 6Division of Medical
Science University of Victoria, Victoria, BC, Canada, 7The Alberta Congenital
Anomalies Surveillance System, Clinical Genetics, Calgary, BC, Canada, 8Division
of Pediatric Surgery, University of British Columbia, Vancouver, BC, Canada, 9BC
Children's Hospital, Vancouver, BC, Canada, 10Deputy Provincial Health
Officer, Office of the Provincial Health Officer, Victoria, BC, Canada, 11Provincial
Health Officer, Office of the Provincial Health Officer, Victoria, BC, Canada. The
British Columbia Congenital Anomalies Surveillance System (BCCASS) Validation
Study
P42
Fernandez
ACG1,2, Padula A1, Basilio E1,
Roger J1, Gaw S1, Robinson JF1. 1University of California, San Francisco, San Francisco, CA, United States,
2University of California, Berkeley, Berkeley, CA, United States. Retrospective
Analysis of Wildfire Smoke Exposure during Pregnancy and Birth Weight Outcomes
P43
Abstract Withdrawn
P44
Hugonin-Rao B1,2.
1Department of Maternal-Fetal Health Azienda USL
Toscana Centro, Florence, Italy, 2Future in Pediatrics, Florence, Naples,
Salerno, Italy. Surveillance of Neural Birth Defects, from
Preconceptional to Perinatal Health: FUTURA Project for a New Challenges for
the Future
P45
Mohan
H1, Nguyen J1, Yee A1, Yukino
Laurette E1, Sanghvi T1, Tejada O1, Mackenzie
B1, Guzman-Lenis M1, Greene N2, Copp A2,
Serghides L1,3. 1Toronto General Hospital Research Institute,
University Health Network, Toronto, ON, Canada, 2Developmental Biology
and Cancer Department, UCL Great Ormond Street Institute of Child Health, University
College London, London, United Kingdom,3Department of Immunology and
Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada. Reproductive
Feto-toxicity Studies to Evaluate Dolutegravir in Combination with
Emtricitabine and Tenofovir in Pregnant Mice on a Folate Deficient Diet
P46
Baier
B, Di Giacomo M, Hugger M.
BI Pharma GmbH & Co KG, Biberach, Germany. Correlation of Body Weight
Changes and Estrous Cycle in Laboratory Rats
P47
Catlin
NR1, Bowman CJ1, Campion SN1,
Nowland WS1, Sathish JG2, Stethem CM1, Updyke LW3,
Cappon GD1. 1Pfizer Worldwide Research, Development, &
Medical, Groton, CT, United States, 2Pfizer Worldwide Research, Development,
& Medical, Pearl River, MS, United States, 3Pfizer Worldwide Research,
Development and Medical, Cambridge, MA, United States. Reproductive
and Developmental Safety of Nirmatrelvir (PF-07321332), an Oral SARS-CoV-2 Mpro
Inhibitor in Animal Models
P48
Shafique
S, Winn L. Queen's University, Kingston, ON, Canada. Histone
Modifications within Murine Decidua Might Play a Role in Valproic Acid-Induced
Teratogenesis
P49
Swenson KS, Bates E. University of Colorado, Anschutz Medical Campus, Aurora, CO, United States. The Effect of Fetal Cannabidiol (CBD) Exposure on Brain Development and Postnatal Behavior
P50
Tayem
Y1, Veeramuthu S1, Rashid A2, Sequeira R1,
Fadel R2. 1Department of Pharmacology and Therapeutics,
Arabian Gulf University, Bahrain, 2Department of Anatomy, Arabian Gulf
University, Bahrain. Effects of Prenatal Administration of Melamine
on Pregnancy Outcome in Rats
P51
Blazejewski
SM, Chapman S, Rendemonti J, Stanislaus
DJ. GSK, Collegeville, PA, United
States. Evaluation of Rabbit Whole Embryo Culture Model as Nonrodent
Alternative for Early Screening
P52
Rychlik
KA, Illingworth E, Sanchez IF,
Attreed SE, Sanchez S, Sillé FC. Johns
Hopkins University Bloomberg School of Public Health, Baltimore, MD, United States.
Arsenic Exposure During Equivalent Second Trimester in C57BL/6 Mouse
Model Leaves Long-Lasting Immune Alterations
P53
Campion
S1, Catlin NR1, Bowman CJ1,
Nowland WS1, Stethem C1, Lewis E2, Cappon G1.
1Pfizer Worldwide Research, Development, &
Medical, Groton, CT, United States, 2Safety Assessment, Charles River
Laboratories, Horsham, PA, United States. The Postnatal Resolution of
Fetal Skeletal Malformations Inducted by Pharmacological DGAT2 Inhibition
during Gestation
P54
Sparks
NR, Williams D, zur Nieden NI.
University of California, Riverside,
CA, Riverside, CA, United States. Mechanisms of Tobacco-Induced Human ESC
Skeletal Developmental Toxicity
P55
Avila-Barnard
SG, Dasgupta S, Cheng V,
Reddam A, Wiegand JL, Volz D. University
of California, Riverside, Riverside, CA, United States. Tris(1,3-dichloro-2-propyl)
Phosphate Disrupts the Normal Trajectory of Cytosine Methylation within
Developing Zebrafish Embryos
P56
Yuan
F, Lu L, Liu J, Chen S-Y. Department
of Pharmacology and Toxicology, Alcohol Research Center, University of Louisville
Health Science Center, Louisville, KY, United States. Reduction in
the Activity of the Putative Enhancers of TFAP2A Contributes to Ethanol-Induced
Impairment of the Migration of Human Neural Crest Cells
P57
Abstract Withdrawn
P58
Afsharian
K1, Trinh V2, Wells PG1,3.
1Dept. of Pharmaceutical Sciences, University
of Toronto, Toronto, ON, Canada, 2Dept. of Biochemistry and Biomedical
Sciences, McMaster University, Hamilton, ON, Canada, 3Dept. of Pharmacology
and Toxicology, University of Toronto, Toronto, ON, Canada. Oxidative
DNA Damage in Fetal Brains of Brca1 Knockout
Mice Following In Utero Ethanol
Exposure
P59
Abstract Withdrawn
P60
Cheng
AP1, Wells PG1,2. 1Dept. of Pharmaceutical Sciences, University of Toronto, Toronto, ON, Canada,
2Dept. of Pharmacology and Toxicology, University of Toronto, Toronto,
ON, Canada. Alterations in Gene Expression Potentially Involved in
Developmental Disorders Caused by Oxidative DNA Damage in Oxoguanine
Glycosylase 1 (Ogg1) Knockout Mice
P61
Chen
H, Kapidzic M, Levan J, Gantar D, Okorie C, Basrai S, Aksel S, Abrahamsson
D, Jigmeddagva U, Buarpung S, San A, Gaw S, Woodruff TJ, Fisher SJ, Robinson JF.
University of California, San Francisco,
San Francisco, CA, United States. Perfluorooctanoic Acid Induces
Transcriptomic Alterations in Primary Human Villous Cytotrophoblasts
P62
Abstract Withdrawn
P63
Chen
H, Kapidzic M, San A, Zeighami
N, Hall S, Fisher S, Robinson JF. University
of California, San Francisco, San Francisco, CA, United States. Perfluorooctanoic
Acid Exposure Alters the Proteome of Primary Human Placental Villous
Cytotrophoblasts