Program
Meeting Agenda
Society for Birth Defects Research and Prevention 2018 Annual Meeting—Mechanisms, Models, Mothers and Babies: Bringing Birth Defects Research into Practice
Only sessions designated with
are eligible for Continuing Medical Education credit.
Chairpersons: Brian Johnson, University of Wisconsin-Madison and Thomas B. Knudsen,
National Center for Computational Toxicology, US EPA
Chairpersons: Christina D. Chambers, University of California–San Diego and Lewis B. Holmes, MassGeneral Hospital for Children
P1 An
In Vitro Screen of a Panel of
Perfluoroalkyl Substances and an In Vivo
Assessment of Effects on Placental and Fetal Growth
Blake BE, Cope H, Fenton SE. Division
of the National Toxicology Program, NIEHS, Research Triangle Park, NC, United States.
P2 Transcriptomic
and Methylomic Profiling of BDE-47 Effects on Human Primary Villous
Cytotrophoblasts
Robinson JF1, Williams Puckett
KA1,2, Kapidzic M1, Hamilton EG1, Chen H1,
Ona K1, Park J-S3, Costello JF4, Fisher SJ1.
1Center for Reproductive Sciences, Department of Obstetrics, Gynecology,
and Reproductive Sciences, University of California–San
Francisco, San Francisco, CA, United States, 2San Francisco State University,
Department of Biology, San Francisco, CA, United States, 3Environmental
Chemistry Laboratory, Department of Toxic Substances Control, Berkeley, CA, United
States, 4Department of Neurological Surgery, University of
California–San Francisco, San Francisco, CA, United States.
P3 Characterization
of Placental Promoter and Imprint Control Regions (ICRs) Reveals Differentially
Methylated Regions across Birthweight Categories
Deyssenroth MA1, Marsit
CJ2, Chen J1, Lambertini L1. 1Icahn
School of Medicine–Mount Sinai,
New York, NY, United States, 2Emory University Rollins School of Public
Health, Atlanta, GA, United States.
P4 Effects
of Quaternary Ammonium Compounds on Expression of Placental Growth Factors and
Cytokines
Payne SE1, Byrd CE1,
Hrubec T1,2. 1Edward via College of Osteopathic Medicine,
Virginia Campus, Blacksburg, VA, United States, 2Virginia-Maryland College
of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg,
VA, United States.
P5 Concentrations
of Selected Heavy Metals in Placental Tissues and Risk of Neonatal Orofacial
Clefts
Pi X1, Ren A1,
Li Z1, Jjin L1, Wang B1. 1Institute
of Reproductive and Child Health, Ministry of Health Key Laboratory of Reproductive
Health, Peking University, Haidian, Beijing, China.
P6 Abstract withdrawn.
P7 Prevalence
of Maternal Marijuana and Tobacco Co-Use through Umbilical Cord Tissue Analysis
Higginbotham AM, Jones JT. United
States Drug Testing Laboratories, Des Plaines, IL, United States.
P8 Smoking
during Pregnancy As a Risk Factor for Development and Severity of Neonatal
Abstinence Syndrome Severity among Newborns Prenatally Exposed to Opioids
Bailey BA, Wood DL, Justice NA,
Shah DS. East Tennessee State University, Johnson City, TN, United States.
P9 Prevalence
and Predictors of Opioid Use during Pregnancy over 15 years in the Québec
Pregnancy Cohort
Sheehy O1, Berthod C2,3,
Bérard A3,4. 1Research Center, CHU Sainte-Justine, Montréal,
QC, Canada 2Faculty of Pharmacy, University of Montréal, Montréal, QC,
Canada, 3Research Center, CHU Sainte-Justine, Montréal, QC, Canada, 4Faculty
of Pharmacy, University of Montréal, Montréal, QC, Canada.
P10 Prevalence
and Determinants of ADHD Medication Use in Québec Children between 1998 and
2015
Boukhris T1,2, Lemelin M1,2,
Sheehy O2, Bérard A1,2. 1University of Montréal,
Montréal, QC, Canada, 2CHU Sainte-Justine Research Center, Montréal,
QC, Canada.
P11 Individual
Benzodiazepine Exposure during Early Pregnancy and the Risk of Spontaneous
Abortion
Zhao J-P1, Sheehy O1,
Bérard A1,2. 1Research Center, CHU Sainte-Justine, Montréal,
QC, Canada, 2Faculty of Pharmacy, University of Montréal, Montréal, QC,
Canada.
P12 Antidepressants
Use during Pregnancy and the Risk of Gestational Diabetes Mellitus
Dandjinou M1,2, Sheehy O2,
Bérard A1,2. 1Faculty of Pharmacy, University of Montréal,
Montréal, QC, Canada, 2CHU Sainte-Justine Research Center, Montréal,
QC, Canada.
P13 Countries
with an Immediate Potential for Primary Prevention of Spina Bifida and
Anencephaly: Mandatory Fortification of Wheat Flour with Folic Acid
Kancherla V. Emory University Rollins
School of Public Health, Atlanta, GA, United States.
P14 Considerations
for Juvenile Spin-Off from a Nonhuman Primate Enhanced Pre-Postnatal
Development Study
York KA1, Chellman GJ2,
Newcomb DL2. 1Charles River Laboratories, Reno, NV, United
States, 2Charles River Laboratories, Reno, NV, United States.
P15 Oxytocin
Priming Facilitates Milk Collection from Long-Tailed Macaques (Macaca fascicularis)
Baker AE1, Edwards J1,
Hustvet D1, Ervin T1, Weinbauer GF2. 1Covance
Laboratories Inc, Madison, WI, United States, 2Covance Preclinical Services,
GmbH, Münster, Germany.
P16 A
Qualification/Feasibility Oral Gavage Study in Neonatal Sprague-Dawley Rats and
CD-1 Mice
Gordon C, Gueorguieva A, Stoute M,
Tavcar R. CiToxLAB North America, Laval, QC, Canada.
P17 Dose
Adjustments and Study Designs for Rodent Juvenile Animal Studies
Posobiec LM, Laffan SB. GlaxoSmithKline,
King of Prussia, PA, United States.
P18 Juvenile
Animal Studies: Suitable Dosing Vehicles and Volumes
Primakova I, Robinson K, Pouliot L.
Charles River Laboratories, Montréal, QC, Canada.
P19 Juvenile
Development of an Antimalarial in the Hra:(NZW)SPF Rabbit As a Model
Andenmatten N1, Marsh K2,
Lewis EM3, Hoberman A3, Mantena R2, Ottinger S4,
Tornesi B2. 1Medicines for Malaria Venture, Geneva, Switzerland,
2AbbVie, North Chicago, IL, United States, 3Charles River
Laboratories, Inc., Horsham, PA, United States, 4Takeda Development Center,
Cambridge, MA, United States.
P20 NTP
Developmental and Reproductive Toxicity Evaluation Data Available in CEBS
(Chemical Effects in Biological Systems) Database
Fostel J1, Lea IA2.
1Division of the National Toxicology Program, NIEHS, Research Triangle
Park, NC, United States, 2ASRC Federal Vistronix, Morrisville, NC, United
States.
P21 Applying
Systematic Review Methods to Identify and Characterize Health Effects of
Diisobutyl Phthalate on the Developing Fetus in Laboratory Animals
Yost EE1, Euling SY2,
Weaver JA1, Beverly B1, Keshava N2, Mudipalli A1,
Arzuaga X2, Blessinger T2, Dishaw L1, Hotchkiss
A1, Makris SL2. 1US Environmental Protection Agency,
ORD, National Center for Environmental Assessment, Research Triangle Park, NC, United
States, 2US Environmental Protection Agency, ORD, National Center for
Environmental Assessment, Washington, DC, United States.
P22 Strategies
and Advancements to Evaluate Developmental Neurotoxicity at the National
Toxicology Program
Ryan KR1, Hsieh J-H1,
Parham F1, Shapiro A1, Sipes N1, Collins B1,
Maull E1, Paules RS1, Walker N1, Behl M1.
1Division of the National Toxicology Program, NIEHS, Research Triangle
Park, NC, United States.
Chairpersons: Natalie Johnson, Texas A&M School of Public Health and Peter H. Langlois, Texas Department of State Health Services
Chairpersons: Evi Struble, US Food and Drug Administration and Susan L. Makris, US Environmental Protection Agency
Chairpersons: Diana Dow-Edwards, SUNY Downstate Medical Center and Grace S. Lee, US Food and Drug Administration
P23 How
Reliable are Preliminary EFD Studies for the Detection of Teratogenicity and
Embryo-Fetal Toxicity?
Barrow P. Roche Pharmaceutical Research
and Early Development, F. Hoffmann-La-Roche Ltd, Basel, Switzerland.
P24 Ensuring
Closure: Defining the End of Dosing in Sprague Dawley Rat and New Zealand White
Rabbit Embryo-Fetal Development Studies
Rayhon SL, Olitan T, Danberry T, Thompson
KE. Bristol-Myers Squibb Company, New Brunswick, NJ, United States.
P25 Syngeneic
vs. Allogeneic Pregnancy in Mice: Impact on Implantation?
Danberry T1, Villano C1,
McElroy P2, Edwards T2, McNerney M1, Thompson KE1.
1Bristol-Myers Squibb Company, New Brunswick, NJ, United States, 2Charles
River Laboratories, Ashland, OH, United States.
P26 Evaluation
of Outbred, Syngeneic, and Allogeneic Pregnancy with Sprague Dawley, F344, and
Lewis Rat Strains
McGlinchey EM1, Edwards
T2, Thompson KE3, Lewis EM1. 1Charles
River Laboratories, Inc., Horsham, PA, United States, 2Charles River
Laboratories, Inc., Ashland, OH, United States, 3Bristol-Myers Squibb
Company, New Brunswick, NJ, United States.
P27 Optimal
Method for Revitalization of Overstained and Under-Cleared Rat Fetuses during
Teratology Studies
Gilmore R, Flavin J, Dandekar D. Xenometrics
LLC, A CiToxLab Group of Companies, Stilwell, KS, United States.
P28 Sensitivity
of Micro-Computed Tomography (micro-CT) Imaging versus Alizarin Red Staining in
Embryo-Fetal Development Toxicity Studies
Quigley KM1, Tatiparthi
AK1, Qualls CD1, Murray KM1, Lewis SL1,
Donahue DA1, Staudner HA1, Weinbauer GF2, Groeller
AK3, Nesbitt NE3. 1Covance Laboratories Inc., Greenfield,
IN, United States, 2Covance Preclinical Services, GmbH, Münster, Germany,
3Covance Laboratories Inc, Greenfield, IN, United States.
P29 Histopathology
from Repeat‑Dose Toxicity Studies Is a Poor Predictor of Rat Female
Fertility Effects in Retrospective Analysis
Laffan SB1, White T2,
Ziejewski MK1, Vidal JD3, Stanislaus DJ1. 1GlaxoSmithKline,
King of Prussia, PA, United States, 2Aclairo Pharmaceutical Development
Group, Vienna, VA, United States, 3MPI Research, Mattawan, MI, United
States.
P30 Rabbit
Fertility Studies: Fact or Fiction
Hershberger SL1, Logsdon
AL1, Saul JC2, Sellers AC1, Sparks-Smith BL1,
White WE1, Staudner HA1. 1Covance Laboratories
Inc., Greenfield, IN, United States, 2Covance Laboratories, Ltd, Harrogate,
NY, United Kingdom.
P31 Catheterization
and Cannulation of the Central Ear Artery of New Zealand White Rabbits for
Toxicokinetic Blood Collections
DeVries KE, McKenna M, Veenstra J.
MPI Research, Mattawan, MI, United States.
P32 Disruption
of Nuclear Receptor Signaling Alters Triphenyl Phosphate-Induced Cardiotoxicity
in Zebrafish Embryos
Mitchell CA1, Dasgupta S2,
Zhang S3, Stapleton H3, Volz DC2. 1Environmental
Toxicology Graduate Program, University of California–Riverside,
Riverside, CA, United States, 2Department of Environmental Sciences,
University of California–Riverside, Riverside,
CA, United States, 3Nicholas School of the Environment, Duke University,
Durham, NC, United States.
P33 Novel
Computational Tools Based on Bioinformatic and Chemoinformatic Data to
Complement Zebrafish Embryo
Teratogenicity Test
Quevedo C1, Muriana A1,
Ipiñazar M1, Planes FJ2, Cendoya X2. 1Biobide,
San Sebastian, Gipuzkoa, Spain, 2TECNUN, University of Navarra, San Sebastian,
Gipuzkoa, Spain.
P34 Niclosamide
Exposure Induces Epiboly Delay during Early-Zebrafish Development
Vliet SM1,2, Dasgupta S2,
Volz DC2. 1Environmental Toxicology Graduate Program, University
of California–Riverside, Riverside, CA,
United States, 2Department of Environmental Sciences, University of California–Riverside, Riverside, CA, United States.
P35 Zebrafish
Genetic Screens Identify Ethanol Susceptibility Loci Necessary for Palate
Development
Lovely CB1,2, Swartz ME2,
Eberhart JK2. 1University of Louisville, Louisville, KY, United
States, 2University of Texas at Austin, Austin, TX, United States.
P36 Zebrafish
Models of FASD: Embryonic Ethanol Exposure Causes Defective Neuronal Migration
Buckley DM, Eberhart JK. University
of Texas–Austin, Austin, TX, United States.
P37 Balancing
the Maternal Microbiota-Perinatal Neuroimmune Axis: Implications for Neurodevelopmental
Disorders
Lebovitz Y1, McDonald V2,
Hrubec T2, Theus M3. 1Virginia Polytechnic
Institute and State University, Blacksburg, VA, United States, 2Edward
Via College of Osteopathic Medicine, Blacksburg, VA, United States, 3Virginia-Maryland
College of Veterinary Medicine, Blacksburg, VA, United States.
P38 Does
Maternal Exposure to Quaternary Ammonium Compounds Affect Inflammatory
Cytokines in the Fetal Mouse Brain?
Byrd CE1, Payne SE1,
Hrubec T1,2. 1Edward via College of Osteopathic Medicine,
Virginia Campus, Blacksburg, VA, United States, 2Virginia-Maryland College
of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg,
VA, United States.
P39 A
Novel Epigenetic Role for the DNA Repair Enzyme Oxoguanine Glycosylase 1 (OGG1)
in Neurodevelopment: Ogg1 Knockout
(KO) Mice Exhibit Decreased DNA Methylation Levels in a Sex- and Brain
Region-Dependent Manner
Bhatia S1, Wells PG2,3.
1Department of Pharmaceutical Sciences and Centre for Pharmaceutical
Oncology, Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada, 2Department
of Pharmacology and Toxicology, Faculty of Medicine, University of Toronto, Toronto,
ON, Canada, 3Department of Pharmaceutical Sciences, Faculty of Pharmacy,
University of Toronto, Toronto, ON, Canada.
P40 Dysfunction
of Isl1 Positive Cardiac Progenitors Contribute to Maternal Diabetes-Induced
Congenital Heart Defects through Cellular Organelle Stress and DNA Hypermethylation
Yang P, Xu C, Yang P. Department of
Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School
of Medicine, Baltimore, MD, United States.
P41 Hypomethylation
of Genes from Several Signaling Pathways and Neural Tube Defects in Association
with Exposure to Polycyclic Aromatic Hydrocarbons
Huang Y, Wang L, Lin S, Jin L, Ren
A. Institute of Reproductive and Child Health, Ministry of Health Key Laboratory
of Reproductive Health, Peking University, Haidian, Beijing, China.
P42 Alterations
in Retinoid Signaling Affect the Development of the Coronary Vasculature
Moise AR1,2,3, Wang S3,4.
1Northern Ontario School of Medicine, Sudbury, ON, Canada, 2Biomolecular
Sciences Program and Department of Chemistry and Biochemistry, Laurentian University,
Sudbury, ON, Canada, 3Department of Pharmacology and Toxicology, School
of Pharmacy, University of Kansas, Lawrence, KS, United States, 4Boston
Children's Hospital, Harvard Medical School, Boston, MA, United States.
P43 Gender
Differences in the Expression of Nervous System Genes in a Mouse Model of
Valproic Acid-Induced Autism-Like Behavior Corrected by S-adenosyl Methionine
Ornoy A1, Weinsteif-Fudim
L1, Ergaz Z2, Yanai J1, Turgeman G3.
1Hebrew University Hadassah Medical School, Jerusalem, Israel, 2Haddasah
University Medical Center, Jerusalem, Israel 3Ariel University, Ariel,
Israel.
P44 Changes
in Cyp2b10 Gene Expression during
Cyclophosphamide Exposure and Maternal Restraint Stress
McCuistion EA1, Mentzer
RW1, Emily M1, Burnett TG1, Hood RD2,
Bailey MM1. 1Emporia State University, Department of Biological
Sciences, Emporia, KS, United States, 2Ronald D. Hood & Associates,
Ponte Vedra, FL, United States.
Chairpersons: Chris J Stodgell, University of Rochester and Susan L. Makris, US Environmental Protection Agency
Chairpersons: Sarah Gloria Običan, University of South Florida and Sonja A. Rasmussen, Centers for Disease Control and Prevention
Chairpersons: Michael D. Collins, University of California–Los Angeles and Grace S. Lee, US Food and Drug Administration
Chairpersons: Russell S. Kirby, USF College of Public Health and Marie McKenzie, University of Georgia
Chairpersons: Barbara R. Hales, McGill University and Kembra L. Howdeshell, National Institute of Environmental Health Sciences
Chairperson: Kenneth Lyons Jones, UCSD, CA MotherToBaby and Elise Madison Lewis, Charles River Laboratories
P45 Development
of a High Throughput-High Content Assay to Identify the Teratogenic Potential
of Organophosphates
Garcia J, Ubina TM, Argueta J, Ashour
A, Bournias-Vardiabasis N. Department of Biology, California State University San
Bernardino, San Bernardino, CA, United States.
P46 A
Human Pluripotent Stem Cell-Based Assay Accurately Predicts the Developmental
Toxicity Potency for a Series of Valproate Analogues
Palmer JA1, Burrier RE1,
Donley E1, Kirchner F1, Kroese D2, Stöber R3,
Churchill Kleinstreuer N4. 1Stemina Biomarker Discovery, Inc.,
Madison, WI, United States, 2TNO, The Hague, South Holland, The Netherlands,
3IfADo– Leibniz Research Centre for Working Environment and Human
Factors, Dortmund, North Rhine-Westphalia, Germany, 4NTP Interagency
Center for the Evaluation of Alternative Toxicological Methods, NIEHS, Research
Triangle Park, NC, United States.
P47 Development
of a Stem Cell-Based Reporter Assay for In
Vitro DART Assessment
Racz PI, Brandsma I, Derr R, Hendriks
G. Toxys BV, Leiden, SH, The Netherlands.
P48 Critical
Window of Sensitivity: Teratogenic Effects of Methotrexate Treatment on GD 12
or 14 in New Zealand White Rabbit
Hill KG, Wahle B, Phipps D, Dandekar
D. Xenometrics LLC, A CiToxLab Group of Companies, Stilwell, KS, United States.
P49 Developmental
Toxicity Study of Polyhexamethylene Guanidine Phosphate in Sprague-Dawley Rats
Exposed by Inhalation
Jeong J-S1, Yu W-J1,
Lee J1, Lee K-H2, Choi S-J2, Yang M-J2,
Lee S-Y1, Park J-D1, Lee S-H2, Bae G-H2.
1Korea Institute of Toxicology, Yuseong, Daejeon, The Republic of Korea,
2Korea Institute of Toxicology, Jeongeup, Jeollabukdo, The Republic of
Korea.
P50 Developmental
and Reproductive Toxicity Studies in Sprague-Dawley Rats and New Zealand White
Rabbits with Palbociclib
Catlin NR1, Bowman CJ1,
Engel SM1, Sacaan A2, Lewis EM3, Cappon GD1.
1Pfizer, Groton, CT, United States, 2Pfizer, La Jolla,
CA, United States, 3Charles River Laboratories, Inc., Horsham, PA, United
States.
P51 Developmental
Toxicity Evaluation of Didecyl Dimethyl Ammonium Chloride (DDAC) in the CD®
(Sprague-Dawley) Rat and New Zealand White Rabbit
Fisher LC, Burruss BL, Hostetler
KA. Toxicology Regulatory Services, A SafeBridge Consultants Company, Charlottesville,
VA, United States.
P52 Developmental
Toxicity Evaluation of Alkyl Dimethyl Benzyl Ammonium Chloride (ADBAC) in the
CD® (Sprague-Dawley) Rat and New Zealand White Rabbit
Fisher LC, Burruss BL, Hostetler KA.
Toxicology Regulatory Services, A SafeBridge Consultants Company, Charlottesville,
VA, United States.
P53 Two-Generation
Reproductive Toxicity Evaluation of Alkyl Dimethyl Benzyl Ammonium Chloride
(ADBAC) and Didecyl Dimethyl Ammonium Chloride (DDAC) in CD®
(Sprague-Dawley) Rats
Fisher LC, Burruss BL, Hostetler KA.
Toxicology Regulatory Services, A SafeBridge Consultants Company, Charlottesville,
VA, United States.
P54 Assessment
of Chlorodibromomethane Effects on Pregnancy Maintenance in a Developmental
Toxicity Screen with F344 Rats
Narotsky MG1, Fuentes L1,2,
Willoughby T2,3. 1US Environmental Protection Agency, ORD,
National Health and Environmental Effects Research Laboratory, Toxicity Assessment
Division, Research Triangle Park, NC, United States, 2Oak Ridge Institute
for Science Education (ORISE), Oak Ridge, TN, United States, 3US Environmental
Protection Agency, ORD, National Health and Environmental Effects Research Laboratory,
Integrated Systems Toxicology Division, Research Triangle Park, NC, United States.
P55 Assessment
of Diiodoacetic Acid Effects on Eye Malformations in a Developmental Toxicity
Screen with F344 Rats
Fuentes L1,2, Narotsky MG2.
1Oak Ridge Institute for Science Education (ORISE), Oak Ridge, TN, United
States, 2US Environmental Protection Agency, ORD, National Health and
Environmental Effects Research Laboratory, Toxicity Assessment Division, Research
Triangle Park, NC, United States.
P56 SCY-078,
a Novel IV/Oral Triterpenoid Antifungal Treatment, Is Not Embryo/Feto-Toxic
Carruthers CM1, Barat S,
Thomas P2, Lewis EM2. 1Scynexis, Inc., Jersey City,
NJ, United States, 2Charles River Laboratories, Inc., Horsham, PA, United
States.
P57 Fetal
Toxicity of Cynara scolymus
Gotardo AT, Mattos MIS, Górniak SL. Research Center of Veterinary Toxicology
(CEPTOX), Department of Pathology, School of Veterinary Medicine and Animal Science,
University of São Paulo, Pirassununga, SP, Brazil.
P58 Investigation
of Pre- and Postnatal Developmental Toxicity of Caffeine in Rats
Yang S1, Ding Z2,
Lei G1, McPherson S1. 1Wuxi Apptec (Suzhou) Co.
Ltd, Suzhou, Wuzhong, China 2WuxiAppTec (Suzhou) Co, Ltd, Suzhou, Wuzhong,
China.
P59 Prenatal
and Early-Life Exposure to Arsenic: Effects on Tuberculosis Pathogenesis
Rychlik KA1, Sanchez I1,
Attreed S1, Sanchez S2, Castriota F2, Zhang H1,
Steinmaus CM2, Smith MT2, Sille F1. 1The
Johns Hopkins University, Baltimore, MD, United States, 2University of
California–Berkeley, Berkeley, CA, United States.
P60 Does
Early-Life Exposure to Estrogenic Chemicals Warrant an Age Dependent Adjustment
Factor in Carcinogen Risk Assessments?
Dai M1, Euling SY2,
Foos B2. 1Oak Ridge Institute for Science and Education, Office
of Children's Health Protection, Washington, DC, United States, 2United
States Environmental Protection Agency, Office of Children's Health Protection,
Washington, DC, United States.
P61 Evaluation
of DART Data Pertaining to Reclassification of Chloroform as a Proposition 65
Reproductive Toxicant
Williams AL1, Bates C1,
DeSesso JM1,2. 1Exponent, Inc., Alexandria, VA, United States,
2Georgetown University School of Medicine, Washington, DC, United States.
P62 The
Epidemiology of Chloroform Exposure and Developmental Outcomes: A Systematic
Review
Pace ND1, Chang ET2,3. 1Exponent, Inc., Oakland,
CA, United States, 2Exponent, Inc., Menlo Park, CA, United States, 3Stanford
Cancer Institute, Stanford, CA, United States.
P63 The
Influence of Pesticides on Birth Defects and Fetal Development at Broad Spatial
Scales
Rumschlag SL, Kirby R, Rohr JR. University
of South Florida, Tampa, FL, United States.
P64 An
Investigation of Racial-Ethnic Disparities in Location of Delivery, Hospital
Transfer, and Survival Among Infants with Congenital Diaphragmatic Hernia
Carmichael SL, Ma C, Shaw GM, Sylvester
KG, Hintz SR. Stanford University, Stanford, CA, United States.
P65 Maternal
Genitourinary Infections and Risk of Birth Defects in the National Birth
Defects Prevention Study
Howley MM1, Feldkamp ML2,
Papadopoulos EA1, Fisher SC1, Arnold KE3, Browne
ML1,4. 1New York State Department of Health, Albany, NY, United
States, 2University of Utah Health Sciences, Salt Lake City, UT, United
States, 3Centers for Disease Control and Prevention, Atlanta, GA, United
States, 4University at Albany School of Public Health, Albany, NY, United
States.
P66 Using
Supervised Machine Learning Methods to Develop a List of Medications of
Greatest Concern during Pregnancy Using Supervised Machine Learning Methods to
Develop a List of Medications of Greatest Concern during Pregnancy
Ailes EC1, Zimmerman J2,
Lind JN1, Fan F2, Shi K2, Reefhuis J1,
Broussard CS1, Frey MT1, Cragan JD1, Petersen EE3,
Polen KD1, Honein MA1, Gilboa SM1. 1National
Center on Birth Defects and Developmental Disabilities, CDC, Atlanta, GA, United
States, 2Deloitte Consulting LLP, New York, NY, United States, 3National
Center for Chronic Disease Prevention and Health Promotion, Atlanta, GA, United
States.
P67 National
Population-Based Estimates for Selected Birth Defects, 2010–2014
Mai C1, Isenburg J1,
Canfield M2, Meyer R3, Alverson C1, Lupo PJ4,
Fox D5, Cho SJ6, Correa A7, Kirby R8.
1Centers for Disease Control and Prevention, Atlanta, GA, United States,
2Texas Department of State Health Services, Austin, TX, United States,
3North Carolina Department of Health and Human Services, Raleigh, NC,
United States, 4Baylor College of Medicine, Houston, TX, United States,
5New York State Department of Health, Albany, NY, United States, 6Minnesota
Department of Health, St. Paul, MN, United States, 7University of Mississippi
Medical Center, Jackson, MS, United States, 8University of South Florida,
Tampa, FL, United States.
P68 How
Does Information about Pregnancy from Social Media Compare to Real-World Data?
Wurst KE, Clayton LM, Powell MS. GlaxoSmithKline,
King of Prussia, PA, United States.
P69 A
Population-Based Analysis of Factors Associated with Timeliness of Surgical
Repair among Infants with Myelomeningocele
Kancherla V1, Ma C2,
Grant G2, Shaw GM2, Hintz SR2, Carmichael SL2.
1Emory University Rollins School of Public Health, Atlanta, GA,
United States, 2Stanford University, Stanford, CA, United States.
P70 Proportion
of Critical Congenital Heart Defects Attributable to Unhealthy Prepregnancy
Body Mass Index among Women with Live Births in Florida, 2004–2013
Lowry J1, Lake-Burger H1,
Salemi J2, Tanner JP3, Kirby R3. 1Florida
Department of Health, Tallahassee, FL, United States, 2Baylor College
of Medicine, Houston, TX, United States, 3University of South Florida,
Tampa, FL, United States.
P71 Abstract withdrawn.
P72 A
Phenotypic Spectrum Overlaps VACTERL and TACRD Associations
Katzman PJ, Patel N, Metlay LA. University
of Rochester Medical School, Rochester, NY, United States.
P73 Normal
and Abnormal Development of Human Stapes and Its Relation to the Middle Ear
Pathologies: A Morphological Approach
Cortés OD, Martinez Burckhartd RJ,
López Serna DMN. Facultad de Medicina de la Universidad Autónoma de Nuevo León,
Monterrey, NL, Mexico.
P74 California:
Pregnancy and Birth Outcomes of Registry-Enrolled Pregnancies Affected by
Travel-Associated Zika Virus Infection
Sowunmi S, Eckert V, Griffin A. California
Birth Defects Monitoring Program, California Department of Public Health, Richmond,
CA, United States.
P75 Density
of CD68+ (Hofbauer) Cells in Zika Infected Placentas
Corchuelo S1, Mercado M2,
Borbon M1, Rico A3, Parra E3, Ospina M4.
1Gesath, Bogotá, DC, Colombia, 2Dirección de Investigación
en Salud Pública, Instituto Nacional de Salud, Bogotá, DC, Colombia, 3Dirección
de Redes en Salud Pública, Instituto Nacional de Salud, Bogotá, DC, Colombia, 4Dirección
General, Instituto Nacional de Salud, Bogotá, DC, Colombia.
P76 The
Use of Metabolomics in the Study of Mild Hypospadias
Pineyro C1, Chorna N2,
Perez-Brayfield MR3, Jorge JC1. 1Department of
Anatomy and Neurobiology, University of Puerto Rico, Medical Sciences Campus, San
Juan, PR, United States, 2Department of Biochemistry,
PR-INBRE Metabolomics Research Center, University of Puerto Rico, Medical Sciences
Campus, San Juan, PR, United States, 3Division of Urology, School of
Medicine, University of Puerto Rico, San Juan, PR, United States.
Chairpersons: Jan M. Friedman, University of British Columbia and Godfrey P. Oakley Jr., Emory University
Chairpersons: Katerine Saili, US Environmental Protection Agency and Mary Alice Smith, University of Georgia
Chairperson: Natasha Catlin, Pfizer, Inc. and Kembra L. Howdeshell, National Institute of Environmental Health Sciences
Chairpersons: Connie L. Chen, ILSI Health and Environmental Sciences Institute and Luc M. De Schaepdrijver, Janssen Research and Development