Program
Meeting Agenda
Society for Birth Defects Research and Prevention 2023 (BDRP)
63rd
Annual Meeting
Improving Pregnancy Outcomes through Collaborative Research
Please note that The times listed are in EDT – Eastern Daylight Time (US).
Organized by the Education Committee,
Chairperson: Wafa A. Harrouk, Center for Drug Evaluation and Research, US FDA
Organized by the Education Committee
Chairperson: Wafa A. Harrouk, Center for Drug Evaluation and Research, US FDA
P1
Chambers CD, Jones KL, Johnson DL, Xu R, Luo Y.
University of California San Diego, La Jolla, CA, United States. Paxlovid Prophylaxis or Treatment
in Pregnancy: Data from the Organization of Teratology Information Specialists (OTIS)
Pregnancy Registry
P2
Rudenb X, Singh A, Rass L, Chakravarty
A, Awonuga AO, Ruden DM, Puscheck EE, Kidder B, Rappolee DA.
Wayne State University, Detroit, MI, United States. Optimization of a Placental TSC
High-Throughput Screen (HTS) that Reports Stress-Forced Stemness Override to Premature
Imbalanced First Lineage Differentiation and Predicts Miscarriage
P3
Sant KE, Wilson PW, Yost J, Navarrete J, Cho CS, Schwartz AV.
San Diego State University, San Diego, CA, United States. Developmental Toxicity of the
Emerging Contaminants Tris(4-Chlorophenyl) Methane (TCPM) and Tris(4-Chlorophenyl)
Methanol (TCPMOH) and Impacts on Pancreatic Organogenesis
P4
Harris SF1, Cunny HC2, Stinson K3, Shockley KR4. 1Social & Scientific Systems, a DLH Holdings Company,
Durham, NC, United States, 2Division of Translational Toxicology, National Institute
of Environmental Health Sciences, Research Triangle Park, NC, United States, 3Southern Research, Birmingham, AL, United States, 4Division of Intramural Research, National Institute
of Environmental Health Sciences, Research Triangle Park, NC, United States. Statistical
Analysis of Fetal Defect Data: A Cautionary Tale
P5
Phanavanh B1, Moore J1, Davis K2, Li X3, Sung K3, Nakamura N1. 1National Center for Toxicological Research, Jefferson,
AR, United States, 2Toxicologic
Pathology Associates, Jefferson, AR, United States, 3Center for Biologics Evaluations and Research, Silver
Spring, MD, United States. Determination of the Effects of Prenatal Remdesivir
Exposure on Placenta Morphology, Placental IgG Transfer, and Fetal Growth in a Humanized
Mouse Model
P6
Fish EW, Vashakidze D, Garcia JV, Benhabbour R, Martina M, Parnell
SE. University of North Carolina, Chapel Hill, NC, United States.
Interaction
between Maternal Diet and the Effects of Prenatal Exposure to a Long-Acting Dolutegravir
Formulation in C57BL/6J Mice
P7
Palmi ER1, Rose CE1, Archer NP2, Broussard CS1, Crider KS1, Green RF3, Olshan AF4, Reefhuis J1, Zarate YA5,6, Ailes EC1. 1National Center on Birth Defects and Developmental Disabilities,
Centers for Disease Control and Prevention, Atlanta, GA, United States, 2Environmental Epidemiology and Disease Registries Section,
Texas Department of State Health Services, Austin, TX, United States, 3Office of Genomics and Precision Public Health, Centers
for Disease Control and Prevention, Atlanta, GA, United States, 4Department of Epidemiology, University of North Carolina,
Chapel Hill, NC, United States, 5Section of Genetics and Metabolism, University of Arkansas
for Medical Sciences, Little Rock, AR, United States, 6Division of Genetics and Metabolism, University of Kentucky,
Lexington, KY, United States. Association between Parental Ages and Birth
Defects
P8
Thai TN1, Maro JC2, Brown J1,3, Schmidt S4, Sonja A Rasmussen5, Winterstein AG1,3,6. 1Department of Pharmaceutical Outcomes and Policy, College
of Pharmacy, University of Florida, Gainesville, FL, United States, 2Department of Population Medicine, Harvard Pilgrim Health
Care Institute and Harvard Medical School, Boston, MA, United States, 3Center for Drug Evaluation and Safety (CoDES), University
of Florida, Gainesville, FL, United States, 4Department of Pharmaceutics, College of Pharmacy, University
of Florida, Gainesville, FL, United States, 5Department of Genetic Medicine, School of Medicine,
Johns Hopkins University, Baltimore, MD, United States, 6Department of Epidemiology, College of Medicine and
College of Public Health and Health Professions, University of Florida, Gainesville,
FL, United States. In Utero Antiemetic Combination during
the First Trimester and Adverse Circulatory Outcomes: A Signal Identification Analysis
P9
Khan NS1,2, Ait Belkacem N1,2, Sheehy O2, Patricia P2, Bérard A1,2. 1University of Montréal, Montréal, QC, Canada. 2CHU Sainte-Justine Research Centre, Montréal, QC, Canada.
COVID-19 during Pregnancy: Prevalence, Predictors, and Impact on the Newborn
P10
Ailes EC, Broussard CS1, Crider KS1, Desrosiers TA2, Gilboa SM1, Howley MM3, Moore C1, Tepper NK1, Waller DK4, Jennita Reefhuis J1. 1National Center on Birth Defects and Developmental Disabilities,
CDC, Atlanta, GA, United States, 2University of North Carolina at Chapel Hill, Chapel
Hill, NC, United States, 3New
York State Department of Health, Albany, NY, United States, 4University of Texas Health Sciences Center at Houston,
Houston, TX, United States. Associations between Antibiotics and Noncardiac
Birth Defects, National Birth Defects Prevention Study and Birth Defects Study to
Evaluate Pregnancy Exposures
P11
Leal LF, Sheehy O, BÉRARD A.
CHU Sainte-Justine Research Centre, Montréal, QC, Canada. The AMerican PREGNANcy-Mother-Child
Cohort (AM-PREGNANT): Description and Prevalence of Main Perinatal Outcomes and
Medication Use
P12
Raskind-Hood CL1, Kancherla V1, Rodriguez FH2, Sullivan AM3, Lui G4, Botto L5, Feldkamp M5, Li J6, D'Ottavio A6, Farr S7, Glidewell J7, Book WM2,1. 1Emory University School of Public Health, Atlanta, GA,
United States, 2Emory University
School of Medicine, Atlanta, GA, United States, 3New York State Health Department, Albany, NY, United
States, 4Divisions of Cardiovascular
Medicine and Pediatric Cardiology, Stanford University School of Medicine, Palo
Alto, CA, United States, 5Division
of Medical Genetics, Department of Pediatrics, University of Utah, Salt Lake City,
UT, United States, 6Duke University
School of Medicine, Durham, NC, United States, 7National Center on Birth Defects and Developmental Disabilities,
Centers for Disease Control and Prevention, Atlanta, GA, United States. Racial/Ethnic
Disparities in Healthcare Utilization and Mortality among Individuals with Documented
Congenital Heart Defects at Healthcare Encounters, Four US Surveillance Sites, 2011–2013
P13
Ephross S, Carneal-Frazer N, Brauneis J, Albano J.
Syneos Health, Morrisville, NC, United States. Abortion-Related Trends before
and after the Dobbs Decision within TriNetX Electronic Medical Record Data
P14
Anderson K, Callaway P.
National Institute for Occupational Safety and Health, Morgantown, WV, United States.
Characterizing
Exposures from N-free Nail Polishes
P15
Lewis EM1, Hoberman AM1, Guenther C2, Bussi S3, Coppo A3, Jones P4, Hirani E4, Fretellier N5. 1Charles River Laboratories, Inc., Horsham, PA, United
States, 2Bayer AG, Berlin, Germany,
3Bracco Imaging Spa, Milano,
Italy, 4GE HealthCare, Chalfont
St Giles, United Kingdom, 5Guerbet,
Roissy, France. Juvenile Toxicity Studies Following Repeated Dose Administrations
of Various Gadolinium (Gd) Based Contrast Agents (GBCAs) to Evaluate Potential Long-Term
Effects and Presence of Gd in the Brain of Male and Female Mice
P16
Palmer JA, Donley ELR.
Stemina Biomarker Discovery, Inc., Madison, WI, United States. Qualification of the devTOX quickPredict Assay for Regulatory Use Under the ICH S5(R3) Guidelines
P17
Lavu A1, Peymani P1, Alessi Severini S1, Ruth C2, Falk J1, Aboulatta L1, Haidar L1, Akinola S1, Farooq F1, Kowalec K1, Derksen S3, Leong C1, Ng M4, Kaul P5, Delaney J1, Eltonsy S1. 1College of Pharmacy, University of Manitoba, Winnipeg,
MB, Canada, 2Max Rady School
of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg,
MB, Canada, 3Manitoba Center
for Health Policy (MCHP), Community Health Sciences, University of Manitoba, Winnipeg,
MB, Canada, 4Section of Neurology,
Department of Internal Medicine, University of Manitoba, Winnipeg, MB, Canada, 5Department of Medicine, Faculty of Medicine & Dentistry,
University of Alberta, Edmonton, AB, Canada. Gabapentin Use during
Pregnancy and Adverse Neonatal Birth Outcomes: A Population-Based Cohort Study
P18
Ewig C1, Muschett M1, Smolinski N1, Thai T1, Rasmussen SA2, Winterstein A1. 1University of Florida, Gainesville, FL, United States,
2Johns Hopkins School of Medicine,
Baltimore, MD, United States. Secular Trends and Determinants of
Hepatitis C Virus Testing during Pregnancy
P19
Yang S, Yan J, Guo L, Pan L, McPherson S.
WuXi AppTec (Suzhou) Co., Ltd., Suzhou, Jiangsu, China. Investigation of Fertility
and Early Embryonic Development to Implantation of Cyclophosphamide in Mice
P20
Singh A1,2, Ruden XL2,3, Marben T4, Tang W5, Feng H5, Awonuga AO2, Ruden DM1,2,6, Puscheck EE2,3,7, Rappolee DA2,3,7. 1Center of Molecular Medicine and Genomics, Wayne State
University, Detroit, MI, United States, 2C. S. Mott Center for Human Growth and Development,
Wayne State University, Detroit, MI, United States, 3Reproductive Stress Inc, Grosse Pointe Farms, MI, United
States, 4University of Detroit
Mercy, Detroit, MI, United States, 5Department of Population and Quantitative Health Sciences,
Case Western Reserve University, Cleveland, OH, United States, 6Institute of Environmental Health Sciences, Wayne State
University, Detroit, MI, United States, 7Invia Fertility, Detroit, United States. A
Single Cell Transcriptomic Fingerprint of Premature, Imbalanced Differentiation
of Embryonic Stem Cells (ESC)
P21
Pique C, Marsden E, Quesada P, Blondel A.
Charles River Laboratories, Lyon, France. A Regulatory Preliminary
Embryo-Fetal Developmental Toxicity Study in the Minipig with Shortened Design
P22
Wiegand J1, Avila-Barnard S1, Nemarugommula C1, Lyons D1, Zhang S2, Stapleton HM2, Volz DC1. 1University
of California, Riverside, Riverside, CA, United States, 2Duke
University, Durham, NC, United States. Triphenyl Phosphate-Induced Pericardial Edema in Zebrafish
Embryos is Dependent on the Ionic Strength of Exposure Media
P23
Mohan H1, Nguyen J1, Sanghvi T1, Tejada O1, Laurette EY1, Guzman-Lenis M1, Greene N2, Copp A2, Serghides L1,3. 1Toronto
General Hospital Research Institute, Princess Margaret Cancer Research Tower (PMCRT),
University Health Network, Toronto, ON, Canada, 2Developmental
Biology and Cancer Department, UCL Great Ormond Street Institute of Child Health,
University College London, London, United Kingdom, 3Department
of Immunology and Institute of Medical Sciences, University of Toronto, Toronto,
ON, Canada. A
Comparative Study of Pregnancy Outcomes in Mice Treated with Integrase Strand
Transfer Inhibitors (INSTI)
P24
Gray RO, Lovely CB.
University of Louisville, Louisville, KY, United States. Characterizing the Ethanol
Sensitivity of the Planar Cell Polarity Pathway in Endoderm Morphogenesis and
Jaw Development
P25
Malin AJ1, Samy S2, Hu H3, Martinez-Mier EA4, Eckel SP3, Farzan SF3, Howe CG5, Funk W6, Habre R3, Bastain TM3, Breton CV3. 1University
of Florida, Gainesville, FL, United States, 2Trace
Organics Analytical Center, University of Washington, Seattle, WA, United States,
3Keck
School of Medicine of USC, Los Angeles, CA, United States, 4School
of Dentistry, Indiana University, Indianapolis, IN, United States, 5Geisel
School of Medicine at Dartmouth College, Lebanon, NH, United States, 6Feinberg
School of Medicine, Northwestern University, Chicago, IL, United States. Urinary Aluminum Levels in
Relation to Urinary Fluoride and Metal Co-exposures among Pregnant Women in Los
Angeles, California
P26
Laham M1,2, Sheehy O2, Mainbourg S2,1, Bérard A1,2. 1Montréal University-Faculty of Pharmacy, Montréal, QC,
Canada, 2Research Centre-CHU
Sainte-Justine, Montréal, QC, Canada. Impact of Levothyroxine Use
during Pregnancy in Hypothyroidism, on Perinatal Outcomes and Child
Neurocognitive Development
P27
Dave AA.
Mercer University School of Medicine, Macon, GA, United States. Vaginitis? It must
Yeast!—Addressing the Negative Impact of Self-Diagnosis of Vulvovaginitis
P28
Gorgui J1, Sheehy O2, Trasler J3, Bérard A1. 1University of Montréal, Montréal, QC, Canada, 2Research Centre-CHU Sainte-Justine, Montréal, QC, Canada.
3RI-McGill University Health
Centre, Montréal, QC, Canada. Trends in Medically Assisted
Reproduction Utilization and Perinatal Outcomes in Quebec between 2005 and
2015: The Impact of the Universal Access Program—An Interrupted Time Series Analysis
P29
Ait Belkacem N1,2, Gorgui J1,2, Lippé S1,2, Bérard A1,2. 1University
of Montréal, Montréal, QC, Canada, 2Research
Center CHU Ste-Justine, Montréal, QC, Canada. Maternal Mental Health during
the COVID-19 Pandemic and Its Impact on Child Cognitive Development
P30
Hall-Lande J1, Pettingell S1, Bershadsky J1, Larson S1, Hallas L1, Riley C2, Liu T2, Reefhuis J2. 1University of Minnesota, Minneapolis, MN, United States,
2Centers for Disease Control
and Prevention, Atlanta, GA, United States. Estimating Prevalence of Spina
Bifida in the US Using Administrative Databases
P31
Smolinski NE, Sarayani A, Thai T, Jugl S, Ewig C, Winterstein AG.
University of Florida, Gainesville, FL, United States. Prenatal Exposure to Valproic
Acid in the United States
P32
Dorsey A1, Downing KF2, Danielson M2, Kancherla V1, Oster ME2,3, Farr S2. 1Department
of Epidemiology, Emory University, Rollins School of Public Health, Atlanta, GA,
United States, 2Centers
for Disease Control and Prevention, National Center on Birth Defects and Developmental
Disabilities, Atlanta, GA, United States, 3Children's
Healthcare of Atlanta and Emory University School of Medicine, Atlanta, GA, United
States. Mental,
Behavioral, and Developmental Disorders (MBDDs) Among US Children with and
without Heart Conditions, 2016–2021
P33
Carter T.
Marshfield Clinic, Marshfield, WI, United States. Identification of Genomic
Regulatory Elements in Human Palatal Mesenchyme Cells
P34
DeSesso JM, Williams AL.
Exponent, Alexandria, VA, United States. Evaluation of the Developmental
and Reproductive Toxicity Potential of Titanium Dioxide
P35
Avila-Barnard SG, Weigand JL, Nemarugommula C, Volz DC.
University of California, Riverside, CA, United States. Tris
(1,3-dichloro-2-propyl)phosphate Disrupts Cellular Metabolism within Human
Embryonic Kidney (HEK293) Cells
P36
Lavu A1, Peymani P1, Alessi-Severini S1, Ruth C2, Falk J1, Haidar L1, Aboulatta L1, Akinola S1, Farooq F1, Kowalec K1, Leong C1, Derksen S3, Ng M4, Delaney J1, Kaul P5, Eltonsy S1. 1College
of Pharmacy, University of Manitoba, Winnipeg, MB, Canada, 2Max
Rady School of Medicine, Rady Faculty of Health Sciences, University of Manitoba,
Winnipeg, MB, Canada, 3Manitoba Center for Health Policy
(MCHP), Community Health Sciences, University of Manitoba, Winnipeg, MB, Canada,
4Section
of Neurology, Department of Internal Medicine, University of Manitoba, Winnipeg,
MB, Canada, 5Department
of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton,
AB, Canada. Antiseizure
Medication Use in Pregnancy and Adverse Neonatal Birth Outcomes: A
Population-Based Cohort Study
P37
Aboulatta L1, Momo K2, Sasaki T2, Tan Q1, Eltonsy S1. 1University of Manitoba, Winnipeg, MB, Canada, 2Showa University, Tokyo, Japan. Stillbirth
Rates before and during the COVID-19 Pandemic in Manitoba (Canada) and Japan
P38
Lowdermilk MM1,2, Evanovich DM1,2, Wang JT2,3, Sadhwani A3,4, Sansevero T5, Zendejas B3,5, Bajic D2,3. 1Tufts University School of Medicine, Boston, MA, United
States, 2Department of Anesthesiology,
Critical Care and Pain Medicine, Boston Children’s Hospital, Boston, MA, United
States, 3Harvard Medical School,
Boston, MA, United States, 4Department of Psychiatry, Boston Children’s Hospital,
Boston, MA, United States, 5Department of Surgery, Esophageal and Airway Treatment
Center, Boston Children’s Hospital, Boston, MA, United States. Growing
Up after Critical Care: Early Neurodevelopmental Outcomes in Esophageal Atresia
P39
Jones KL, Chambers CD.
University of California San Diego, La Jolla, CA, United States. Considering Fetal Alcohol
Spectrum Disorders as a Mitigating Factor in Death Row Cases in the US
P40
Williams AL, DeSesso JM.
Exponent, Alexandria, VA, United States. An Extended One-Generation
Reproductive Toxicity Study (EOGRT) of Food-Grade Titanium Dioxide
P41
Yaye AB1, Lemma TB2. 1Dire Dawa University, Dire Dawa, Ethiopia, 2Jimma University, Jimma, Ethiopia. Effect
of Picture-Based Health Education and Counselling on Knowledge and Adherence to
Preconception Iron-Folic Acid Supplementation among Women Planning to Be
Pregnant in Eastern Ethiopia: A Randomized Controlled Trial
P42
Shafique S, Bile C, Winn L.
Queen's University, Kingston, ON, Canada. Investigating the Effect of In
Utero Benzene Exposure on mRNA and Protein Expression of Xrcc4, Xrcc5,
Xrcc6, Rad51, and BRCA2 Genes in Murine Placenta
P43
Davis D1, Hrubec TC1,2, Kula J1, Kirkpatrick Z2. 1Edward Via College of Osteopathic Medicine, Blacksburg,
VA, United States, 2Virginia-Maryland
College of Veterinary Medicine, Blacksburg, VA, United States. Morphological
Differences in Mouse Embryos Following Quaternary Ammonium Compound Exposure
P44
Ghaffari R, Biven M, Albert A, Dong J.
Corteva Agriscience, Newark, DE, United States. Characterization of Maternal
Liver Enzyme Induction Effects on Thyroid-Related Endpoints in Offspring
P45
Fitzpatrick HT1, Wolf CJ2. 1ORISE, Oak Ridge, TN, United States, 2Environmental Protection Agency, ORD, CPHEA, Research
Triangle Park, NC, United States. Antineoplastic and Antiepileptic
Agents Inhibit Fusion in 3D Organotypic Human Palate Fusion Model
P46
Cen R1, Ying J1, Nembhard W1, Goudie A1, El-hassan N2. 1University of Arkansas for Medical Sciences College
of Public Health, Little Rock, AR, United States, 2University of Arkansas for Medical Sciences, Arkansas
Children's Hospital, Little Rock, AR, United States. Hospital
Readmission within Five Years after Surgical Repair among Infants Born with
Esophageal Atresia and/or Tracheoesophageal Fistula in Arkansas
P47
Bérard A1,2, Sheehy O2, Kaul P3, Eltonsy S4, Walker M5, Hawken S6, Bernatsky S7, Pugliese M6, Barrett O8, Savu A3, Dragan R4. 1University of Montréal, Montréal, QC, Canada, 2Research Centre-CHU Ste-Justine, Montréal, QC, Canada,
3University of Alberta, Edmonton,
AB, Canada. 4University of Manitoba,
Winnipeg, MB, Canada, 5The Ottawa
Hospital, Ottawa, ON, Canada, 6The Ottawa Hospital Research Institute, Ottawa, ON,
Canada, 7McGill University,
Montréal, QC, Canada. 8Alberta
Health Services, Edmonton, Alberta, Canada. COVID-19 Infection and
Medicines in Pregnancy in Canada
P48
Maibourg S1, Sheehy O2, Vinet E3, Bérard A2,1. 1Université
de Montréal, Montréal, QC, Canada, 2Centre de Recherche CHU Sainte
Justine, Montréal, QC, Canada, 3Mc Gill University, Montréal,
QC, Canada. Prevalence
and Use of Medications for Autoimmune Diseases during Pregnancy
P49
Gorgui J1,2, Tchuente V2, Pagès N2,3, Fareh T2,3, Elgbeili G4, King S4, Bérard A1,2. 1University of Montréal, Montréal, QC, Canada, 2Research Centre-CHU Sainte-Justine, Montréal, QC, Canada.
3Université Claude Bernard-Lyon
1, Lyon, France, 4McGill University,
Montréal, QC, Canada. The Impact of Prenatal Maternal Mental Health
during the COVID-19 Pandemic on Birth Outcomes: A Study within CONCEPTION
Cohort
P50
Wiesel A, Ma X, DiDomenico J, Wohler F, Roberts MH, Bakhireva
LN. Substance Use Research and Education Center, University of New
Mexico, Albuquerque, NM, United States. Dose-Response Effect of
Prenatal Alcohol Exposure on Perinatal Outcomes
P51
Forestieri NE1, Olshan AF2, Oster ME3, Ailes EC4, Fundora MP4, Fisher SC5, Shumate C6, Romitti PA7, Liberman RF8, Nembhard WN9, Carmichael SL10, Desrosiers TA2. 1Birth Defects Monitoring Program, State Center for Health
Statistics, Division of Public Health, North Carolina Department of Health and Human
Services, Raleigh, NC, United States, 2Department of Epidemiology, Gillings School of Global
Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United
States, 3Division of Pediatric
Cardiology, Children’s Healthcare of Atlanta; and School of Medicine, Emory University,
Atlanta, GA, United States, 4Division of Birth Defects and Infant Disorders, National
Center on Birth Defects and Developmental Disabilities, Centers for Disease Control
and Prevention, Atlanta, GA, United States, 5Birth Defects Research Section, New York State Department
of Health, Albany, NY, United States, 6Birth Defects Epidemiology and Surveillance Branch,
Texas Department of State Health Services, Austin, TX, United States, 7Department of Epidemiology, College of Public Health,
University of Iowa, Iowa City, IA, United States, 8Massachussets Center for Birth Defects Research and
Prevention, Massachusetts Department of Public Health, Boston, MA, United States,
9Department of Epidemiology,
College of Public Health; and Department of Pediatrics, College of Medicine, University
of Arkansas for Medical Sciences, Little Rock, AR, United States, 10Departments of Pediatrics and Obstetrics & Gynecology,
Stanford University School of Medicine, Stanford, CA, United States. Survival
of Children with Critical Congenital Heart Defects in the National Birth
Defects Prevention Study
P52
Zhu Y1,2, Hernandez-Diaz S3, Anand P2, Bykov K2,1, Sarpatwari A1,2, Mahesri M2, DiCesare E2, Vine S2, Mogun H2, Huybrechts K1,2. 1Harvard
Medical School, Boston, MA, United States, 2Brigham
and Women’s Hospital, Boston, MA, United States, 3Harvard
T.H. Chan School of Public Health, Boston, MA, United States. Assessment of the
Effectiveness of Risk Evaluation and Mitigation Strategy for the Prevention of
Fetal Exposure to Phentermine-Topiramate Using Two Large Nationwide Cohorts
P53
Potineni H, Happ HH, Carvill GL. Northwestern
University Feinberg School of Medicine, Chicago, IL, United States. Using Cell-Free DNA to Detect
Brain-Specific Variants in Epilepsy
P54
Stanislaus D1, Romach B2, Ziejewski M1. 1GlaxoSmithKline, Collegeville, PA, United States, 2ViiV Healthcare, Raleigh, NC, United States.
Cabotegravir: Absence of Reproductive and Developmental Toxicity in Animal
Studies
P55
Vannappagari V1,2, Albano JD3, Thorne C4, Ragone L1, Scheuerle AE5, Cook T3, Zhang C3, Rasi V4, de Ruiter A6, Giaquinto C7. 1ViiV Healthcare, Durham, NC, United States, 2Gillings School of Global Public Health, University
of North Carolina, Chapel Hill, NC, United States, 3Syneos Health, Wilmington, NC, United States, 4University College London Great Ormond Street Institute
of Child Health, London, United Kingdom, 5University of Texas Southwestern Medical Center, Dallas,
TX, United States, 6ViiV Healthcare,
London, United Kingdom, 7University
of Padova, Padova, Italy. Pregnancy and Neonatal Outcomes Following
Prenatal Exposure to Cabotegravir (CAB): Data from the Antiretroviral Pregnancy
Registry (APR) and European Pregnancy and Paediatric HIV Cohort Collaboration
(EPPICC)
P56
Yuan F, Liu J, Chen S-y. Department of Pharmacology and
Toxicology, University of Louisville Alcohol Research Center, University of Louisville
Health Sciences Center, Louisville, KY, United States. Ethanol-Induced Dysregulation
of Enhancers and Aberrant Expression of Their Cognate Genes Contribute to
Craniofacial Defects in Zebrafish Embryos
P57
Ireland D, Miller J.
CDH International, Wake Forest, NC, United States. Congenital Diaphragmatic
Hernia: Patient Parents as Partners
P58
Sheehy O1, Eltonsy S2, Hawken S3,4, Walker M5, Kaul P6, Winquist B7, Barrett O8, Savu A6, Dragan R9, Pugliese M4, Bernatsky S10, Gorgui J1,11, BÉRARD A1,11,12. 1Research Centre, CHU Sainte-Justine, Montréal, QC, Canada,
2University of Manitoba, College
of Pharmacy, Winnipeg, MB, Canada, 3University of Ottawa, Clinical Epidemiology, Ottawa,
ON, Canada, 4ICES uOttawa, Ottawa,
ON, Canada, 5University of Ottawa,
Faculty of Medicine, Ottawa, ON, Canada, 6University of Alberta, Faculty of Medicine and Dentistry,
Edmonton, AB, Canada. 7Saskatchewan
Health Authority, Saskatoon, SK, Canada, 8Alberta Health Services, AHS Data and Analytics, Calgary,
AB, Canada, 9University of Manitoba,
Manitoba Centre for Health Policy, Winnipeg, MB, Canada, 10McGill University, Faculty of Medicine, Montréal, QC,
Canada, 11University of Montréal,
Faculty of Pharmacy, Montréal, QC, Canada. 12University of Claude Bernard, Faculty of Medicine, Lyon,
France. Health Canada Advisory Impact on the Prevalence and Trends of
Oral Codeine Use in the Pediatric Canadian Population: A Comparative Study
across Provinces
P59
Rayhon SL1, Mulatu S2, Thompson KE1, Turner KJ1. 1Janssen,
Spring House, PA, United States, 2Texas A&M University, College
Station, TX, United States. A Retrospective Analysis of Fertility Assessments for
Monoclonal Antibodies in Sexually Mature Nonhuman Primates