Teratology Society

Members' Section

1998 Meeting Highlights

PLEASE NOTE THAT A FULL DAY IS SCHEDULED FOR THURSDAY

Why Attend the 1998 Teratology Meeting?
The Teratology Society Annual Meeting provides the attendees with comprehensive coverage of teratology - abstracts plus scientific sessions present "cutting-edge" research. The Meeting provides attendees with an opportunity to network with leading scientists. Low registration fees make the Meeting cost-effective, providing participants with an opportunity to benefit from high-quality scientific sessions while gaining exposure to the latest advances in the science, at an inexpensive price. The Teratology Exhibition offers one-stop shopping from suppliers, where attendees gain first-hand knowledge about the products and services of participating exhibitors.

The Scientific Program Committee has assembled an impressive group of keynote speakers, major symposia, and session papers. There will be a Warkany Lecturer and four major symposia, including Genetic Susceptibility to Teratogenesis, sponsored by the March of Dimes; the NICHD Symposium, Genomics in Birth Defect Research; Normal and Abnormal Genital Development, co-sponsored by Wiley-Liss and the Midwest Teratology Association; and The New Thalidomide Era: Dealing with the Risks, sponsored by the Public Affairs Committee of the Teratology Society. In addition, a workshop entitled, Dungeons and Dragons: A Game for Teratologists of all Ages, sponsored by Quintiles, will be held on Thursday, June 25, from 7:00 p.m. to 10:00 p.m. We will have four platform sessions that will feature over 30 papers. We will also have a poster session on Tuesday, June 23, 1998. At this time, we will be able to view and discuss our own posters and posters of the Neurobehavioral Teratology Society, (NBTS). Special non-concurrent student presentations will be presented on Tuesday, June 23, 1998, and pre-selected presentations, (pre- and post-doctoral) will be presented at a single platform session; these will be papers competing for awards. Please attend and show support or our students.

The San Diego Princess is located in the center of San Diego, on a forty-acre island in Mission Bay, only 8 minutes from the San Diego International Airport. Within 45 minutes or less from the resort, are the following attractions: Sea World, Wild Animal Park, San Diego Zoo at Balboa Park and historic Old Town. On site are five pools (two heated); six lighted championship tennis courts; an innovative 18-hole golf course; a sand volleyball court; a 1.3-mile running course; a full-service marina, featuring a wide selection of sailboats, catamarans and powerboats; a state-of-the-art fitness center; and over a mile of white sand beach for swimming and sunbathing. The resort is surrounded by parkland filled with bicycle and walking paths. There are over 20 world-class golf courses within a short drive.

The San Diego Princess Resort offers a variety of guest accommodations representing the ultimate in luxury, charm and ambience. All accommodations are single-level and offer a variety of layouts, with either patios, gardens, lagoon or bay views. In addition to the lanai guest rooms, a selection of luxurious studio and one-bedroom suites are also available. Guestroom amenities include remote-controlled cable television and movies, refrigerator, in-room coffee service and adjacent complimentary parking.

The Teratology Society has reserved a block of rooms at the Princess. All attendees who make room reservations by May 25, 1998, will be entered into a drawing for a one-year FREE membership in the Teratology Society and a FREE copy of John Gerhart's book, Cells, Embryos, Evolution: Toward a Cellular and Phenotypic Variation and Evolutionary Adaptability. Dr. Gerhart is this year's Warkany Lecturer. Please complete the enclosed Accommodation Reservation Request Form on page 19 and mail or fax to the hotel by May 25th.

If you require special services, please mark the appropriate box on the Accommodation Reservation Request Form. If you require more information about disabled access, please contact the hotel at (619) 274-4630.

All rooms are subjected to 10.5% sales tax. All rooms must be guaranteed and will be credited to the last night of the reservation request. An early checkout will forfeit deposit.

The deadline for advanced registration for the 1998 Teratology Society Annual Meeting is May 25, 1998. After May 25, 1998, a late fee of $40 will apply.

Registration is open from Saturday, June 20 through Thursday, June 25 in the Pacific Ballroom Foyer.

WHAT DOES THE REGISTRATION FEE INCLUDE?
The Registration Fee includes entrance to all scientific sessions and presentations, all social functions, the exhibit area, and the following food events:

• Welcome Buffet (Saturday)
• President's Reception (Sunday)
• Warkany Tea (Tuesday)
• Banquet Reception and Banquet (Wednesday)
• Wilson Luncheon (Thursday)
• Continental Breakfasts (Monday-Thursday)
• Refreshment Breaks (Monday-Thursday)

The Accompanying Person Registration Fee includes all social functions and continental breakfasts. The Accompanying Child Registration Fee includes the above, with a child's size portion for the Banquet and Wilson Luncheon.

WHAT DOES THE SINGLE-DAY REGISTRATION FEE INCLUDE?
The Single-Day Registration Fee includes entrance to all scientific sessions and presentations, social functions, the exhibit area, and any of the above food events taking place ON THE DAY OF REGISTRATION.

Oral Presentations
Each platform paper, except for those presented in the symposia, will be allowed 15 minutes (12 minutes for presentations and 3 minutes for discussion). The time schedule will be strictly followed. Projectors for 35mm slides will be available in each meeting room. Please keep slides simple and uncluttered. A good rule of thumb is, if you cannot read your slide without magnification, those in the middle and rear of the room will be unable to read it when presented. One concept per slide and a maximum rate of one slide per minute, are also good rules to follow for effective presentations.

Poster Presentations
Poster material should be organized within a 4 ft. x 8 ft. area. The top of your poster board should contain the following information, with letters at least 3/4 inches high:

1. Your poster number
2. Title
3. Authors
4. Affiliations

A copy of the abstract should be posted towards the upper-left corner, and a set of conclusions toward the lower- right corner of your poster. These should be printed in letters about 1/4 inch high. Poster information should be legible from a distance of at least 3 to 4 feet. Material, including line drawings, should be clearly presented and may be computer generated (laser printer is preferable). PLEASE BRING YOUR OWN PUSH PINS. Poster sessions and times for setup and removal are indicated in the Program.

Posters should be on display from 7:00 a.m. to 11:00 p.m. on Monday, June 22 and 7:00 a.m. to 7:00 p.m. Tuesday, June 23. Those presenting posters should plan to be present on Tuesday evening at the following times: Even Numbered Posters, 8:00 p.m. - 9:30 p.m.; Odd Numbered Posters, 9:30 p.m. - 11:00 p.m., when time has been scheduled for posters to be viewed. All posters should be removed on Tuesday, June 23, 1998, immediately following the Poster Session (11:00 p.m.).

In an effort to assist graduate students and postdoctoral fellows to attend the Annual Meeting, the Teratology Society will make available a limited number of Travel Awards. These awards, designed to help defray a portion of the cost of travel to the meeting, will be presented to awardees during the Wilson Luncheon on Thursday, June 25, 1998, 11:30 a.m. to 1:00 p.m. In addition, a limited number of Travel Fellowships for minority students, will also be awarded.

Those graduate students or postdoctoral fellows wishing to be considered for these travel awards should send 1) a letter of application from their research advisor or director and 2) five copies of any abstract submitted for presentation at this year's meeting to:

Alan G. Fantel, Ph.D.
Chair, Student Affairs Committee
Research Professor
University of Washington
Department of Pediatrics - Box 356320
Birth Defects Laboratory
Seattle, WA 98195-6320
T: 206-543-3373
F: 206-543-3184
E-mail: agf@u.washington.edu

Selection of travel award recipients will be by the Student Affairs Committee of the Teratology Society.
DEADLINE for receipt of applications: May 20, 1998.

Shopping, Dining and Sightseeing
Meteorologists have long agreed that San Diego has a perfect climate, but the real beauty of a San Diego visit comes from the endless variety of activities, attractions and amenities to be enjoyed. There are 70 miles of Pacific Ocean beach, two sparkling bays, several uplifting mountain ranges, a breathtaking desert, and an international border, all within one spectacular area—San Diego.

Visit the world famous San Diego Zoo, or browse through the dozens of museums with exhibits ranging from fine art and natural history to aircraft and sports memorabilia. Take the time to explore Old Town which offers the flavor of Mexico in an authentic early San Diego setting.

If this isn't your first visit to San Diego, you still have plenty of surprises in store. Downtown San Diego is an exciting, constantly changing showplace of department stores, world famous specialty shops, restaurants, galleries and theatres. The Gas Lamp Quarter has been restored to turn-of-the-century elegance, while several more blocks are filled with a multi-level center, Horton Plaza, featuring more than 150 stores. Along the harbor, the waterfront theme village continues to grow with more cruises and water taxis; experience the popular ferry rides to Coronado. And, for an extra bonus, take a short trolley ride to a visit south of the border to Mexico.

Air Transportation
This year, we are using LEE TRAVEL for airline reservations. Lee Travel's toll-free number is: (800) 303-4251. Attendees using Lee Travel when making their reservations will receive discounted airfares on United Airlines and American Airlines for travel originating in the U.S. and Canada. These rates provide a savings of 5% off the lowest applicable fare. Also, you can take advantage of additional savings by staying over Saturday night. When making reservations through Lee Travel, use the Travel Form on page 17.

Ground Transportation
The San Diego International Airport is located approximately 10 to 15 minutes from the San Diego Princess Resort and transportation is provided by shuttle or taxi service. Shuttles pick up outside the baggage claim area of the airport. The Cloud Nine Shuttle Service is available from the airport for $8 one-way. Taxicabs from the San Diego Airport to the hotel run between $10 and $14 one-way.

The San Diego Wild Animal Park is the greatest outdoor wildlife display in the world. You will have the opportunity to observe large herds of wild animals from the safety of a monorail and during cocktails in the Mombasa Outdoor Pavilion while interacting with a number of small exotic animals and birds of prey. Following dinner , Dr. Kurk Benirschke will present a talk entitled, Conservation in Paraguay: Saving the Nearly Extinct Chacon Giant Peccary. The cost of $53.00 will include a chartered bus to and from the park, admission to the park, a monorail ride, and dinner.

Exhibit Space
The Teratology Society Exhibition provides scientists with a unique experience to learn more about state-of-the-art products and to socialize during the reception hosted in the exhibit area. At the Exhibition, scientists will have a first-hand opportunity to talk with the exhibitors and examine the products and services on display by a variety of companies. To request a booth at the Teratology Exhibition, contact Clarissa Russell Wilson at Society Headquarters: (703) 438-3104, ext. 326.

Event-sponsoring opportunities are available for the 1998 Teratology Society Annual Meeting. Events to be sponsored include:

Saturday, June 20	Welcome Buffet
Sunday, June 21	President's Reception
Monday, June 22	Past President's Luncheon
Tuesday, June 23	Warkany Tea
Wednesday, June 24	President's Circle Reception Banquet Reception, and Banquet
Thursday, June 25	Wilson Lunch
June 20 through June 25	Continental Breakfasts & Refreshment Breaks

Participating companies will be recognized in the Teratology Program, the May-June and/or July-August Teratology newsletters, and through signage on-site. If you are interested in Teratology sponsorship, please contact Teratology Society Headquarters at (703) 438-3104 for a complete list of available opportunities.

Saturday June 20, 1998

11:00 am - 5:00 pm	Registration
11:00 am - 5:00 pm	Council IA meeting
1:00 - 5:00 pm	Continuing Education Course
5:00 - 6:30 pm	Free time
6:30 - 10:00 pm	Welcome buffet

Sunday June 21, 1998

7:30 - 8:00 am	Continuing education course continental breakfast
7:30 am - 5:00 pm	Registration
7:45 am - 12:00 pm	Council IB meeting
8:15 am - 12:00 pm	Continuing education course
12:00 - 1:15 pm	Lunch (on you own)
1:15 - 5:00 pm	Public Affairs Committee Symposium The New Thalidomide Era: Dealing with the Risks
1:15 - 1:30 pm	Introduction Jan Friedman M.D., Ph.D., Chair, Public Affairs Committee
1:30 - 2:15 pm	Thalidomide Then and Now - An FDA Perspective Debra Birnkrant, M.D., Chairperson, FDA Thalidomide Working Group
2:15 - 3:00 pm	Celgene's Fetal Protection Program Bruce Williams, Vice President, Sales and Marketing, Celgene Corporation
3:00 - 3:30 pm	Break
3:30 - 4:15 pm	Ethical Issues in the Marketing of Thalidomide Norman Fost M.D., Ph.D., Department of Pediatrics, University of Wisconsin Hospital
4:15 - 5:00 pm	Ethical and Moral Issues from a Thalidomider's Point of View Randall Warren, CEO, The Thalidomide Victim's Association of Canada
5:00 - 6:00 pm	Free time
6:00 - 7:00 pm	President's reception
7:30 - 11:00 pm	Strategic Planning Committee Meeting

Monday June 22, 1998

7:00 - 7:45 am	Continental breakfast
7:30 am - 5:00 pm	Registration
7:45 - 8:00 am	President's Welcome and Introduction Dr. Philip E. Mirkes, President, Teratology Society
8:00 - 8:45 am	Warkany lecture Signal Transduction Pathways in Development Dr. John Gerhart, University of California, Berkeley, CA
8:45 am - 12:30 pm	March of Dimes/NBTS Symposium Genetic Susceptibility to Teratogenesis
8:45 - 9:00 am	Introduction Rick Finnell, Texas A&M University, College Station
9:00 - 9:45 am	Clinical Evidence for Genetic Differences in Susceptibility Ed Lammer, Children's Hospital, Oakland
9:45 - 10:30 am	Strain Differences in Susceptibility to Valproic Acid-induced Exencephaly in Mice Joseph Nadeau, Genetics Department, Case Western Reserve University
10:30 - 11:00 am	Break
11:00 - 11:45 am	Genetic Analysis of Paw Usage Behavior in the Mouse as a Model for Handedness Fred Biddle, University of Calgary
11:45 am - 12:30 pm	Population-based Data on Susceptibility to Birth Defects Elisabeth Robert, Institut Europeen des Genomutations, Lyon
12:00 - 6:00 pm	Unattended Posters
12:30 - 2:00 pm	Lunch (on your own) Past Presidents' Luncheon (by invitation)
2:00 - 3:30 pm	Platform I: OTIS/Teratology Society joint session Chairs: Kenneth L. Jones and William F. Rayburn
3:30 - 4:00 pm	Break
4:00 - 5:00 pm	Legal case discussions Chair: Anthony R. Scialli
6:00 - 10:00 pm	Trip to Wildlife Park (optional)

Tuesday June 23, 1998

7:00 - 7:45 am	Continental breakfast
7:30 am - 2:30 pm	Registration
7:45 - 11:30 am	NICHD Symposium Genomics in Birth Defect Research
7:45 - 8:00 am	Introduction Thomas B. Knudsen, Jefferson Medical College
8:00 - 8:45 am	Overview of the Human Genome Project Eric Green, Chief of the Genome Technology Branch, National Human Genome Research Institute
8:45 - 9:30 am	From Maps to Medicine: Identification of Candidate Genes for DiGeorge (DGS) and Velocardiofacial Syndrome (VCFS) Beverly Emanuel, Children's Hospital of Philadelphia
9:30 - 10:00 am	Break
10:00 - 10:45 am	Mapping Regions of Identity between Complex Genomes Stanley F. Nelson, Department of Pediatrics, UCLA Medical Center
10:45 - 11:30 am	Genome Information in Toxicology Research Richard J. Bull, National Environmental and Molecular Sciences Laboratory, Richland
11:30 am - 1:00 pm	Lunch (on your own) Committee meetings MARTA / MTA lunch
1:00 - 3:00 pm	Platform II: Student presentations Chair: John Gerhart, Warkany Lecturer
3:00 - 3:30 pm	Warkany tea
3:30 - 5:00 pm	Teratology society business meeting
5:00 - 6:00 pm	Open forum
6:00 - 8:00 pm	Dinner (on your own)
8:00 - 9:30 pm	Poster sessions: Even numbered posters - attended
9:30 - 11:00 pm	Poster sessions: Odd numbered posters - attended
11:00 pm	Posters removed

Wednesday June 24, 1998

7:00 - 8:00 am	Continental breakfast
7:00 - 8:00 am	Exhibitor breakfast
7:30 am - 5:00 pm	Registration
8:00 - 11:30 am (Break 9:30 - 10)	Poster Discussion Workshops A. Arsenic Chairs: Ronald D. Hood and Richard K. Miller B. Modeling and Monitoring Risk Chairs: William Slikker and Anne Pastuszak C. Molecular Biology Chairs: Barbara F. Hales and L. David Wise
11:30 am - 1:00 pm	Lunch (on your own) Reproductive Toxicology Board Meeting
1:00 - 3:00 pm	Platform III Clinical Teratology and Epidemiology Chairs: John Harris and Elisabeth Robert
3:00 - 3:30 pm	Break
3:30 - 5:00 pm	Discussion session Has the teratology study design prevented another thalidomide or have we just been lucky? Chair: Thomas J. Flynn
3:00 - 6:30 pm	Exhibit removal
5:00 - 6:30 pm	Free time
6:30 - 7:30 pm	Banquet Reception
7:30 - 10:00 pm	Banquet
7:30 - 10:00 pm	President's Circle Reception (invitation only)

Thursday June 25, 1998

7:00 - 7:45 am	Continental breakfast
7:30 am - 4:00 pm	Registration
7:45 - 11:30 am	Wiley-Liss Symposium Normal and Abnormal Genital Development Organized and cosponsored by the Midwest Teratology Association
7:45 - 8:00 am	Introduction David Clarke, Lilly Research Laboratories, Greenfield
8:00 - 8:45 am	Development of the Genital System: Embryology and Anatomy Kok-Wah Hew Ph.D., Novartis Pharmaceuticals Corporation, East Hanover NJ
8:45 - 9:30 am	The Molecular Basis of Vertebrate Sex Determination Rosamund Smith, Ph.D., Lilly Research Laboratories, Greenfield IN
9:30 - 10:00 am	Break
10:00 - 10:45 am	Abnormal Genital Development: Structural and Functional Abnormalities Tamara Greco, Ph.D., Biology Dept., Eastern Michigan University, Ypsilanti MI
10:45 - 11:30 am	Clinical Management of Congenital Genital Defects George Kaplan, M.D., San Diego CA
10:30 am - 12:30 pm	Student Presentations
11:30 am - 1:00 pm	Wilson luncheon
1:00 - 3:00 pm	Platform IV: Mechanisms of Abnormal Development Chairs: Harpal Buttar and Karen Augustine
3:00 - 3:30 pm	Break
3:30 - 5:00 pm	Platform V: Neural Tube Defects Chairs: Diana M. Juriloff and James L. Schardein
5:00 - 7:00 pm	Council II
7:00 - 10:00 pm	Dungeons and Dragons: A Game for Teratologists of all Ages Sponsored by Quintiles

The Continuing Education Course offering this year is Development and Function of Endocrine and Immune Systems in Teratology. The Education Committee has put together an ambitious curriculum in this area, that has never been the subject of a Teratology Society course. Tuition for the course has not been changed from previous years and our course remains one of the world's best bargains in continuing education. The course will be offered on Saturday afternoon, June 20 and Sunday morning, June 21.

Development and Function of Endocrine and Immune Systems in Teratology

Saturday June 20, 1998

1:00 - 1:05 pm	Welcome - Philip E. Mirkes, Ph.D., President, Teratology Society
1:05 - 1:15 pm	Introduction and Orientation Craig Harris, Ph.D., Chairman, Education Committee
1:15 - 2:00 pm	Overview of the Development and Function of Endocrine Systems Tamara McNutt, Augusta State University

Development, Function and Teratology of the Neuroendocrine Axis

2:00 - 2:45 pm	Pituitary Phil Gage, University of Michigan
2:45 - 3:30 pm	Thyroid Susan Porterfield, Medical College of Georgia
3:30 - 3:45 pm	Coffee Break
3:45 - 4:30 pm	Glucocorticoids Ted Slotkin, Duke University

Overview - Effects of Endocrine Disruptors on Targets in Addition to Reproductive Organs

4:30 - 5:15 pm

Endocrine Disruption Earl Gray, U.S. Environmental Protection Agency

Sunday June 21, 1998

7:30 - 8:00 am	Continental Breakfast
8:00 - 8:45 am	Overview of the Development and Function of the Immune System Dwayne Hill, University of Michigan
8:45 - 9:30 am	Methods for Evaluation of Effects of Chemicals on the Developing Immune System - Dioxins Nancy Kerkvleit, Oregon State University
10:15 - 10:30 am	The Role of the Immune System in Diethylstilbestrol Teratogenicity Steven Holladay, Virginia Tech
10:15 - 10:30 am	Coffee Break
10:30 - 11:15 am	DiGeorge Sequence - Abnormal Formation of the Thymus Ed Lammer, Oakland Children's Hospital
11:15 am - 12:00 pm	Environmental Effects on Immune System Development Rod Dietert, Cornell University
12:00 pm	Adjournment